VIDEO: States with lower health, socioeconomic ranking have higher IBD-related mortality
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Key takeaways:
- U.S. states in the lowest quartile for all aggregate factors and health outcomes had higher mortality rates.
- IBD mortality correlated with overall health factors and behaviors as well as socioeconomic factors.
VANCOUVER, British Columbia — Researchers found significant associations between state-level health disparities and poor inflammatory bowel disease-related outcomes, with low-ranking states demonstrating higher mortality rates.
“I was working in an IBD clinic, and I noticed how different patients have completely different outcomes — even if they’re the same age, the same race,” Manasik Abdu, MD, PGY-3 chief resident in the department of internal medicine at the University of Buffalo, said in a Healio video exclusive. “There were some things that didn’t make sense for me.”
To better understand state-level health disparities and their impact on IBD outcomes, Abdu and colleagues obtained IBD-related mortality data from CDC WONDER, as well as state socioeconomic data, physical environment, clinical care and health behaviors from America’s Health Rankings, provided by United Health Foundation. They categorized states into quartiles based on rankings.
According to a poster presented at the ACG Annual Scientific Meeting, analysis revealed a significantly higher overall mortality rate per 1,000,000 people among states in the lowest quartile for all aggregate factors (incidence rate ratio = 35.99; 95% CI, 2.01-646.18), health outcomes (IRR = 32.28; 95% CI, 1.81-576.7), clinical care (IRR = 82.82; 95% CI, 4.68-1,465.9) and health behaviors (IRR = 59.34; 95% CI, 3.34-1,055.73).
In addition, z-score analysis showed significant correlation between IBD mortality and overall health factors (RR = 1.253; 95% CI, 1.023-1.534) and health behaviors (RR = 1.211; 95% CI, 1.057-1.386), as well as social and economic factors (RR = 1.236; 95% CI, 1.006-1.517).
Researchers also reported that women had higher age-adjusted mortality rates compared with men, and white individuals had higher mortality rates (10.85; 95% CI, 5.07-16.63) compared with Black individuals (5.7; 95% CI, 2.84-8.56).
“Our study showed that states that have lower health factors had higher mortality rate from IBD,” Abdu concluded. “It’s very important to look at states that had lower health factors, and then try to see why that is and what we can do about it.”
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Abdu M, et al. Inflammatory bowel disease mortality is associated with state-level health disparity in the United States. Presented at: ACG Annual Scientific Meeting; Oct. 20-25, 2023; Vancouver, British Columbia (hybrid meeting).
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