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Stomach/Duodenum News
Angiotensin receptor blockers ‘may not be safe,’ worsen outcomes for celiac disease
PHILADELPHIA — Angiotensin receptor blockers were associated with worse outcomes in patients with celiac disease, including anemia, iron deficiency and “continued mucosal damage in the small intestine,” according to a presenter.
Duodenal mucosal renewal plus semaglutide may lower HbA1c long term without insulin use
A novel duodenal mucosal renewal procedure followed by once-weekly semaglutide could allow adults with type 2 diabetes to maintain glycemic control without insulin therapy, according to a speaker.
Bariatric surgery cuts pancreatic cancer risk for adults with or without type 2 diabetes
Adults with obesity who underwent bariatric surgery were less likely to develop pancreatic cancer than those who with obesity who did not have bariatric surgery, researchers reported.
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Prepregnancy bariatric surgery tied to ‘overall downward shift’ in infant growth
Prepregnancy bariatric surgery was linked to lower risks for gestational hypertension, large for gestational age infants and gestational diabetes but increased risks for preterm birth and small for gestational age infants, data show.
Decreases in BMI, HbA1c with diabetes drugs can lower cardiometabolic disease risks
Decreases in body weight and HbA1c induced by GLP-1 receptor agonists and other diabetes drugs can reduce the risk for cardiometabolic complications for adults newly diagnosed with type 2 diabetes, researchers reported.
Q&A: What is driving ‘disturbing’ rise in metastatic stomach cancer in young adults?
In 2021, Jessica Sheth Bhutada, MD, MS, and colleagues uncovered a startling 2% annual uptick in metastatic stomach cancer in young adults, despite declining rates in older adults. Three years later, they are still trying to understand why.
New guideline highlights ‘individualized approach’ in management of chronic constipation
An updated clinical practice guideline from The American Society of Colon and Rectal Surgeons underscored the need for collaborative, cross-specialty care to achieve “optimal patient outcomes” in chronic constipation.
‘Bad guys’ in the gut: Archaea overgrowth linked to severe constipation
The prevalence and severity of constipation was significantly higher in patients with intestinal methanogen overgrowth, underscoring the importance of diagnostic and treatment strategies specific to archaea overgrowth, researchers wrote.
Vanda’s tradipitant falls short for gastroparesis as FDA requests ‘additional studies’
The FDA has issued a complete response letter to Vanda Pharmaceuticals indicating it cannot approve the company’s new drug application seeking approval for tradipitant as a treatment for gastroparesis.
Benefits of weight loss from bariatric surgery extend to blood pressure control
Bariatric surgery for weight loss was associated with improvements in blood pressure and antihypertensive use among patients with obesity compared with medical therapy and/or lifestyle management, a speaker reported.
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