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Liver/Biliary Disorders News
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Oral vancomycin may offer ‘viable option’ for IBD-related primary sclerosing cholangitis
Oral vancomycin therapy resulted in clinical response in nearly half of patients with inflammatory bowel disease associated with primary sclerosing cholangitis, according to a study published in Therapeutic Advances in Gastroenterology.
Genetic risk scores for insulin resistance tied to cardiometabolic measures for children
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Genetic risk scores for predicting insulin resistance that were developed for adults are also tied to some cardiometabolic metrics in children and adolescents, according to study findings.
Q&A: Surgeon General’s warning exposes public ‘knowledge gap’ of alcohol links to cancer
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There are approximately 100,000 alcohol-related cancer cases annually in the U.S. and 20,000 deaths due to alcohol-related cancer, according to an HHS press release.
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US cases of MASLD projected to top 121 million by 2050 alongside 55% spike in MASH
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A new model has projected a substantial rise in the burden of metabolic dysfunction-associated steatotic liver disease in the U.S. by 2050, which could be minimized by effective preventive and management strategies, researchers wrote.
Q&A: Dry January trend ‘could be a wake-up call’ on risk for alcohol-related liver disease
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Dry January has become an increasingly popular trend in which people abstain from alcohol use for 1 month to reset their health after the holiday season. But, for some, it could be a wake-up call about their struggles with alcohol.
AGA urges antiviral prophylaxis for patients at high risk for hepatitis B reactivation
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In a new clinical practice guideline, the AGA provided evidence-based recommendations for either antiviral prophylaxis or continued surveillance to manage hepatitis B virus reactivation in patients receiving immunosuppressive therapy.
Chronic HBV treatment with xalnesiran plus immunomodulator confers highest HBsAg loss
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Treatment with xalnesiran, a small interfering RNA molecule, plus an immunomodulator resulted in hepatitis B surface antigen loss among adults with chronic HBV infection, according to a study published in The New England Journal of Medicine.
Q&A: Prenatal chemical exposure linked to liver injury in mothers, children 10 years later
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Exposure to environmental chemicals during pregnancy may increase the risk for liver injury and steatosis in children and mothers, which could be mitigated by higher folic acid supplementation, according to a study in Journal of Hepatology.
Q&A: First paired liver donation at Mayo a ‘significant first step’ to improving care
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The success of Mayo Clinic’s first paired living-donor liver transplantation may pave the way for expanded access and more “timely transplant” for patients in need, Timucin Taner, MD, PhD, told Healio.
Bluejay Therapeutics’ brelovitug secures FDA breakthrough status for chronic HDV
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The FDA has granted breakthrough therapy designation to Bluejay Therapeutics’ brelovitug for the treatment of chronic hepatitis delta, for which no approved therapies currently exist in the U.S., the company announced in a press release.
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