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Pancreatic Disorders News
Zegocractin ‘holds promise’ for reducing organ failure, necrosis in acute pancreatitis
PHILADELPHIA —Higher doses of zegocractin significantly reduced severe organ failure and necrotizing pancreatitis in patients with acute pancreatitis and systemic inflammatory response syndrome, according to late-breaking data.
Fewer deaths in pulmonary embolism plus pancreatic cancer cases in 2020 vs. 2001
BOSTON — Fewer patients hospitalized for acute pulmonary embolism with pancreatic cancer died in 2020 compared with rates in 2001, according to a presentation at the CHEST Annual Meeting.
‘Significant’ savings with diclofenac vs. indomethacin for post-ERCP pancreatitis
PHILADELPHIA — No significant differences were observed in post-endoscopic retrograde cholangiopancreatography pancreatitis with prophylactic diclofenac vs. indomethacin, with researchers also reporting savings of nearly $133,000.
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‘No observed increase’ in pancreatic cancer among patients with type 2 diabetes on GLP-1RAs
PHILADELPHIA — Patients with type 2 diabetes on glucagon-like peptide-1 receptor agonists had significantly lower risk for pancreatic cancer compared with those on other antidiabetic therapies, regardless of weight, according to data.
AI model highly accurate in differentiating pancreatic cystic, solid lesions on ultrasound
PHILADELPHIA — An AI model achieved high accuracy in detecting and distinguishing between cystic and solid pancreatic focal lesions during endoscopic ultrasound procedures, according to data presented at the ACG Annual Scientific Meeting.
Bariatric surgery cuts pancreatic cancer risk for adults with or without type 2 diabetes
Adults with obesity who underwent bariatric surgery were less likely to develop pancreatic cancer than those who with obesity who did not have bariatric surgery, researchers reported.
Competing-risk model provides more accurate estimate of transplant waiting time
A simple median waiting time that did not account for censoring, death and other competing events underestimated time to organ transplantation by up to 61% compared with a competing-risk model, according to a study conducted in Switzerland.
Plozasiran lowers triglycerides, reduces pancreatitis risk in chylomicronemia
In patients with persistent chylomicronemia, plozasiran, a small interfering RNA therapy, was associated with lower triglyceride levels and reduced risk for pancreatitis, researchers reported at the European Society of Cardiology Congress.
Tirzepatide tied to lower odds for diabetic retinopathy, pancreatitis than GLP-1s
Tirzepatide is associated with similar odds for gastrointestinal adverse events and a lower likelihood for diabetic retinopathy and pancreatitis compared with GLP-1 receptor agonists, according to a presenter.
Plozasiran secures FDA breakthrough status for FCS, closing gap with rival olezarsen
The FDA has granted breakthrough therapy designation to Arrowhead Pharmaceuticals’ plozasiran, coupled with diet, to decrease triglycerides in patients with familial chylomicronemia syndrome, according to a company release.
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