Motility News

PHILADELPHIA — An ingestible gas-sensing capsule from Atmo Biosciences showed “substantial agreement” with the discontinued Medtronic wireless motility device for measuring regional transit times in gastrointestinal motility disorders.

Daily consumption of Bifidobacterium animalis subsp lactis HN019 did not increase complete spontaneous bowel movements per week vs. placebo in healthy individuals with functional constipation, according to a study in JAMA Network Open.

An updated clinical practice guideline from The American Society of Colon and Rectal Surgeons underscored the need for collaborative, cross-specialty care to achieve “optimal patient outcomes” in chronic constipation.

The prevalence and severity of constipation was significantly higher in patients with intestinal methanogen overgrowth, underscoring the importance of diagnostic and treatment strategies specific to archaea overgrowth, researchers wrote.

The FDA has issued a complete response letter to Vanda Pharmaceuticals indicating it cannot approve the company’s new drug application seeking approval for tradipitant as a treatment for gastroparesis.

Occasional bloating is common in most individuals, but for some, aging can contribute to an increase in gas as gastrointestinal motility slows, leading to an uptick in bloating and other GI symptoms.

Every August, gastrointestinal care providers and patient advocacy groups celebrate Gastroparesis Awareness Month, an annual campaign focused on improving understanding of gastroparesis and promoting preventive strategies.

Patients with acute gastroenteritis had up to fourfold increased odds for developing postinfection irritable bowel syndrome or functional dyspepsia, with a higher risk associated with proinflammatory microbes and SARS-CoV-2, data showed.

The AGA has published a clinical practice update highlighting the need for awareness and “prompt recognition” of cyclical vomiting syndrome to effectively diagnosis and treat patients.