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Motility News

Children, teens face 25% higher risk for adverse GI outcomes after COVID-19 infection
Children and adolescents with documented postacute COVID-19 syndrome experienced increased risk for gastrointestinal symptoms and disorders, according to a study published in JAMA Open Network.
Medicare selects 15 drugs for second round of price negotiations, including semaglutide

CMS has selected 15 new drugs for the next round of Medicare Part D price negotiations, according to a press release from HHS.
Prucalopride still effective in CIC despite older age, unhealthy BMI or renal impairment

Prucalopride was safe and effective in increasing the frequency of complete spontaneous bowel movements in patients with chronic idiopathic constipation, regardless of age, BMI or renal function, according to data.
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Constipation Awareness Month seeks to ‘normalize conversations about digestive health’

Although constipation affects millions of people worldwide, it remains one of the least discussed health concerns due to social stigma, according to a press release from the International Foundation for Gastrointestinal Disorders.
Angiotensin receptor blockers ‘may not be safe,’ worsen outcomes for celiac disease

PHILADELPHIA — Angiotensin receptor blockers were associated with worse outcomes in patients with celiac disease, including anemia, iron deficiency and “continued mucosal damage in the small intestine,” according to a presenter.
Atmo capsule may offer ‘potential replacement’ for nixed SmartPill in motility disorders

PHILADELPHIA — An ingestible gas-sensing capsule from Atmo Biosciences showed “substantial agreement” with the discontinued Medtronic wireless motility device for measuring regional transit times in gastrointestinal motility disorders.
No difference in stool frequency with B. lactis HN019 vs. placebo in constipation

Daily consumption of Bifidobacterium animalis subsp lactis HN019 did not increase complete spontaneous bowel movements per week vs. placebo in healthy individuals with functional constipation, according to a study in JAMA Network Open.
New guideline highlights ‘individualized approach’ in management of chronic constipation

An updated clinical practice guideline from The American Society of Colon and Rectal Surgeons underscored the need for collaborative, cross-specialty care to achieve “optimal patient outcomes” in chronic constipation.
‘Bad guys’ in the gut: Archaea overgrowth linked to severe constipation

The prevalence and severity of constipation was significantly higher in patients with intestinal methanogen overgrowth, underscoring the importance of diagnostic and treatment strategies specific to archaea overgrowth, researchers wrote.
Vanda’s tradipitant falls short for gastroparesis as FDA requests ‘additional studies’

The FDA has issued a complete response letter to Vanda Pharmaceuticals indicating it cannot approve the company’s new drug application seeking approval for tradipitant as a treatment for gastroparesis.
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Headline News
Cancer surgeon runs the globe to raise testicular cancer awareness
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Headline News
Cancer surgeon runs the globe to raise testicular cancer awareness
March 21, 20258 min read -
Headline News
FDA launches online database for chemical containment levels in food
March 20, 20251 min read -
Headline News
‘Early events’ can increase a person’s risk for long COVID
March 20, 20253 min read