Motility News

Prucalopride was safe and effective in increasing the frequency of complete spontaneous bowel movements in patients with chronic idiopathic constipation, regardless of age, BMI or renal function, according to data.

Although constipation affects millions of people worldwide, it remains one of the least discussed health concerns due to social stigma, according to a press release from the International Foundation for Gastrointestinal Disorders.

PHILADELPHIA — Angiotensin receptor blockers were associated with worse outcomes in patients with celiac disease, including anemia, iron deficiency and “continued mucosal damage in the small intestine,” according to a presenter.

PHILADELPHIA — An ingestible gas-sensing capsule from Atmo Biosciences showed “substantial agreement” with the discontinued Medtronic wireless motility device for measuring regional transit times in gastrointestinal motility disorders.

Daily consumption of Bifidobacterium animalis subsp lactis HN019 did not increase complete spontaneous bowel movements per week vs. placebo in healthy individuals with functional constipation, according to a study in JAMA Network Open.

An updated clinical practice guideline from The American Society of Colon and Rectal Surgeons underscored the need for collaborative, cross-specialty care to achieve “optimal patient outcomes” in chronic constipation.

The prevalence and severity of constipation was significantly higher in patients with intestinal methanogen overgrowth, underscoring the importance of diagnostic and treatment strategies specific to archaea overgrowth, researchers wrote.

The FDA has issued a complete response letter to Vanda Pharmaceuticals indicating it cannot approve the company’s new drug application seeking approval for tradipitant as a treatment for gastroparesis.

Occasional bloating is common in most individuals, but for some, aging can contribute to an increase in gas as gastrointestinal motility slows, leading to an uptick in bloating and other GI symptoms.