Liver Injury/Regeneration News

Hospitals that performed at least 25 major hepatectomies per year had lower rates of postoperative in-hospital mortality and failure to rescue, suggesting better management of postoperative complications.

CHARLOTTE, N.C. — A subgroup analysis of liver transplant patients with hepatorenal syndrome type 1 demonstrated that terlipressin decreased the need for renal replacement therapy up to 12 months following transplantation.

WASHINGTON — Prednisone induced a higher 90-day survival rate and lower incidence of acute kidney injury compared with anakinra and zinc sulfate in patients with severe alcohol-associated hepatitis, according to late-breaking data.

In this Healio video, Andrew J. Costandi, MD, MMM, details the Enhanced Recovery After Liver Transplantation protocol at Children’s Hospital Los Angeles, which shortened post-transplant ICU stays from 7 to 3 days in pediatric patients.

Evening chronotype was associated with more severe nonalcoholic fatty liver disease independent of age, sex and BMI compared with morning chronotype among adults with obesity, according to data published in International Journal of Obesity.

New research has linked the incidence of unexplained hepatitis in pediatric patients to a pair of viruses — adenovirus type F41 and adeno-associated virus 2 — as well as potential markers of genetic mutation.

Receiving an mRNA or inactivated COVID-19 vaccine did not increase the risk for acute liver injury, according to a study published in Journal of Hepatology.

A noninvasive liquid biopsy test diagnosed the presence and severity of nonalcoholic steatohepatitis and liver fibrosis more reliably than liver biopsy, according to research published in Gut.

Healio handpicked its top stories on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, which highlight risks for children with NAFLD, how fatigue relates to quality of life, treatment with resmetirom and more.

LONDON — Longitudinal serum alanine aminotransferase trajectories remained stable over time among a subset of patients with nonalcoholic fatty liver disease, according to research presented at the International Liver Congress.