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Liver Injury/Regeneration News

FDA approves first treatment for rare lipid storage disease
The FDA has approved Ctexli for the treatment of cerebrotendinous xanthomatosis (CTX), a rare lipid storage disease, in adults.
Q&A: Prenatal chemical exposure linked to liver injury in mothers, children 10 years later

Exposure to environmental chemicals during pregnancy may increase the risk for liver injury and steatosis in children and mothers, which could be mitigated by higher folic acid supplementation, according to a study in Journal of Hepatology.
Early renal replacement therapy improves survival in acute liver failure, cerebral edema

SAN DIEGO — Preemptive continuous renal replacement therapy after therapeutic plasma exchange reduced mortality and improved other outcomes in patients with acute liver failure and cerebral edema, according to data from The Liver Meeting.
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#OctoberIs4Livers campaign draws awareness to health inequities in liver cancer care

Every October marks Liver Cancer Awareness Month in an effort to raise awareness and improve advocacy and treatment for patients living with the disease.
Mental health concerns reduce likelihood of hepatology referral in alcohol use disorder

Nearly two-thirds of patients with excessive alcohol use and a high fibrosis-4 index were not referred for liver-related care, with fewer referrals among those with mental health disorders or alcohol-related mental health hospitalizations.
Nearly 15.6 million Americans using botanical supplements may be at risk for liver injury

Researchers estimated that nearly 15.6 million Americans consumed at least one potentially hepatotoxic botanical product in the past 30 days, similar to usage reports for simvastatin and NSAIDS.
Liver transplant bests chemotherapies for improved survival in colorectal liver metastasis

Patients who underwent liver transplantation vs. alternative therapy for unresectable colorectal liver metastasis had higher progression-free and overall survival, as well as lower rates of recurrence, researchers reported in JAMA Surgery.
Prevalence of cirrhosis ‘more than double’ in transgender vs. cisgender adults

Transgender adults had “more than double” the prevalence of cirrhosis vs. cisgender adults, as well as higher rates of comorbidities linked to liver disease progression, researchers reported in The American Journal of Gastroenterology.
Fazirsiran lowers serum, liver concentrations of Z-AAT in alpha-1 antitrypsin deficiency

In a dose-dependent manner, fazirsiran reduced serum and liver concentrations of Z-AAT and also improved histological measures in patients with homozygous ZZ alpha-1 antitrypsin deficiency-associated liver disease, according to data.
ACG recommends full patient workup, evaluation to differentiate focal liver lesions

In a new clinical practice guideline, the ACG has provided evidence-based recommendations for the diagnosis and management of the most common focal liver lesions among individuals without known liver disease.
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Headline News
Societies take stand against off-brand GLP-1s over safety concerns
March 17, 202515 min read -
Headline News
THA stem design may have a larger impact on periprosthetic fracture risk vs. cement use
February 06, 20251 min read -
Headline News
Self-perceived stress linked to cryptogenic ischemic stroke in young women
March 14, 20253 min read
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Headline News
Societies take stand against off-brand GLP-1s over safety concerns
March 17, 202515 min read -
Headline News
THA stem design may have a larger impact on periprosthetic fracture risk vs. cement use
February 06, 20251 min read -
Headline News
Self-perceived stress linked to cryptogenic ischemic stroke in young women
March 14, 20253 min read