Liver Injury/Regeneration News

SAN DIEGO — Preemptive continuous renal replacement therapy after therapeutic plasma exchange reduced mortality and improved other outcomes in patients with acute liver failure and cerebral edema, according to data from The Liver Meeting.

Every October marks Liver Cancer Awareness Month in an effort to raise awareness and improve advocacy and treatment for patients living with the disease.

Nearly two-thirds of patients with excessive alcohol use and a high fibrosis-4 index were not referred for liver-related care, with fewer referrals among those with mental health disorders or alcohol-related mental health hospitalizations.

Researchers estimated that nearly 15.6 million Americans consumed at least one potentially hepatotoxic botanical product in the past 30 days, similar to usage reports for simvastatin and NSAIDS.

Patients who underwent liver transplantation vs. alternative therapy for unresectable colorectal liver metastasis had higher progression-free and overall survival, as well as lower rates of recurrence, researchers reported in JAMA Surgery.

Transgender adults had “more than double” the prevalence of cirrhosis vs. cisgender adults, as well as higher rates of comorbidities linked to liver disease progression, researchers reported in The American Journal of Gastroenterology.

In a dose-dependent manner, fazirsiran reduced serum and liver concentrations of Z-AAT and also improved histological measures in patients with homozygous ZZ alpha-1 antitrypsin deficiency-associated liver disease, according to data.

In a new clinical practice guideline, the ACG has provided evidence-based recommendations for the diagnosis and management of the most common focal liver lesions among individuals without known liver disease.

Researchers have developed a data-driven, systematic approach for classification of the most potentially hepatotoxic medications based on incidence rates of severe acute liver injury, rather than published case report counts.