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Transplantation News
ZIP code, social vulnerability affect access to liver transplant in alcohol-related disease
Most recipients of early liver transplant for severe alcohol-related liver disease live in close proximity to transplant centers, which are more likely to be in socially advantaged areas, according to research in Gastro Hep Advances.
Women 8% less likely than men to receive a liver transplant, possibly due to candidate size
Women with hepatocellular carcinoma were less likely to receive a liver transplant and more likely to die or be removed from the waitlist vs. men, underscoring the need for changes to allocation policies, according to researchers.
Liver transplant bests chemotherapies for improved survival in colorectal liver metastasis
Patients who underwent liver transplantation vs. alternative therapy for unresectable colorectal liver metastasis had higher progression-free and overall survival, as well as lower rates of recurrence, researchers reported in JAMA Surgery.
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Risk score has ‘superior ability’ to predict LT waitlist dropout among patients with HCC
A continuous risk score accurately predicted waitlist dropout and post-liver transplantation outcomes in patients with hepatocellular carcinoma, even over the course of several UNOS policy changes, researchers reported.
New LT allocation policy increases cost by 10.9% overall, 13.9% in underserved areas
The new United Network for Organ Sharing liver allocation policy has resulted in a significant increase in the number and cost of liver imports, with greater costs incurred by low-income states and underserved areas, according to analysis.
Research highlights ‘serious unmet need’ for LT in severe acute-on-chronic liver failure
Interim results from a global, multicenter study demonstrated the benefit of liver transplantation among patients with acute-on-chronic liver failure grades 2 and 3 and suggest that current allocation systems are inadequate.
FMT safe, ‘could prevent’ recurrence of hepatic encephalopathy in patients with cirrhosis
Recurrence of hepatic encephalopathy was lower among patients with cirrhosis and hepatic encephalopathy who received oral capsule or enema fecal microbiota transplant vs. placebo, according to research from EASL Congress.
VIDEO: Women, Black patients underrepresented in US-based clinical trials for LT
WASHINGTON — In a Healio video exclusive, Saqr Alsakarneh, MD, MSc, describes “significant disparities” in race, ethnicity and sex among participants enrolled clinical trials for liver transplantation in the U.S.
Fewer complications with normothermic regional perfusion vs. super rapid recovery LT
Recipients of livers recovered by normothermic regional perfusion vs. standard super rapid recovery experienced lower rates of ischemic cholangiopathy and biliary complications, with comparable patient and graft survival, data showed.
Nearly 90% of liver transplant center websites still use alcohol-stigmatizing language
A “vast majority” of liver transplant centers use stigmatizing language, such as “alcoholic” or “alcohol abuse,” when describing patients with alcohol use disorder and alcohol-associated liver disease on their websites, researchers reported.
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