Liver Injury/Regeneration News

A noninvasive liquid biopsy test diagnosed the presence and severity of nonalcoholic steatohepatitis and liver fibrosis more reliably than liver biopsy, according to research published in Gut.

Healio handpicked its top stories on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, which highlight risks for children with NAFLD, how fatigue relates to quality of life, treatment with resmetirom and more.

LONDON — Longitudinal serum alanine aminotransferase trajectories remained stable over time among a subset of patients with nonalcoholic fatty liver disease, according to research presented at the International Liver Congress.

LONDON — Lower fatigue scores at baseline correlated with adverse clinical events among patients with advanced nonalcoholic steatohepatitis, according to research presented at the International Liver Congress.

LONDON — Cirrhosis severity, infections and mortality outcomes were worse for patients in low to middle-income countries, due in part to poor access to liver transplant and ICU facilities, according to data presented here.

LONDON — Ozempic improved cardiometabolic parameters and markers of liver injury yet failed to improve liver fibrosis in patients with nonalcoholic steatohepatitis and compensated cirrhosis, according to late-breaker data presented here.

LONDON — Support vector machines had the highest accuracy in predicting liver decompensation among a subset of patients in Germany compared with other machine learning models, according to data presented at the International Liver Congress.

LONDON — Lower MELD score predicted short- and long-term survival in patients with severe alcohol-associated hepatitis who were declined for early liver transplantation, according to research presented at the International Liver Congress.

LONDON — Patients who received a liver transplant had significantly reduced antibody and T-cell responses to SARS-CoV-2 vaccination compared with healthy controls, according to research presented at the International Liver Congress.

LONDON — Nonalcoholic fatty liver disease and alcohol-associated liver disease are among the main contributors of increased mortality related to chronic liver disease and liver cancer burden, according to research.