Cirrhosis/Liver Failure News

SAN DIEGO — Patients with decompensated alcohol-associated cirrhosis and ascites taking naltrexone had lower risk for all-cause mortality and liver disease complications, including acute kidney injury and spontaneous bacterial peritonitis.

SAN DIEGO — Glucagon-like peptide-1 receptor agonists may help alleviate risk for adverse liver outcomes, particularly hepatic decompensation, among patients with type 2 diabetes and alcohol-associated liver disease.

SAN DIEGO — Increasing the mean arterial pressure target to 75 mmHg lowered the odds of 28-day mortality by 85%, and also reduced the odds of acute kidney injury nonrecovery, in decompensated cirrhosis with septic shock, according to data.

SAN DIEGO — Preemptive continuous renal replacement therapy after therapeutic plasma exchange reduced mortality and improved other outcomes in patients with acute liver failure and cerebral edema, according to data from The Liver Meeting.

PHILADELPHIA — In this video, Paul Kwo, MD, professor of medicine and director of hepatology at Stanford University, speaks with Healio about the underutilization of palliative care for patients with end-stage liver disease.

PHILADELPHIA — In this video, Paul Kwo, MD, professor of medicine and director of hepatology at Stanford University, highlights a presentation evaluating the use of sodium-glucose cotransporter 2 inhibitors in patients with cirrhosis.

PHILADELPHIA — Patients with cirrhosis had an increased risk for bleeding within 30 days of colorectal endoscopic mucosal resection compared with controls, although the need for reintervention or ICU admission was similar between groups.

PHILADELPHIA — Rifaximin monotherapy reduced episode recurrence and “may confer” a survival benefit compared with lactulose monotherapy among patients with cirrhosis and a history of overt hepatic encephalopathy, according to a presenter.

A diagnostic tool based on speech variables helped identify minimal hepatic encephalopathy and may predict time to development of overt hepatic encephalopathy in patients with cirrhosis, according to a study published in Hepatology.