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Liver/Biliary Disorders News
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Injectable naltrexone tops disulfiram, acamprosate as safer option in alcohol use disorder
Injectable naltrexone had a more favorable gastrointestinal and liver safety profile compared with other medications for alcohol use disorder, according to a research letter published in Clinical Gastroenterology and Hepatology.
Oral vancomycin may offer ‘viable option’ for IBD-related primary sclerosing cholangitis
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Oral vancomycin therapy resulted in clinical response in nearly half of patients with inflammatory bowel disease associated with primary sclerosing cholangitis, according to a study published in Therapeutic Advances in Gastroenterology.
Genetic risk scores for insulin resistance tied to cardiometabolic measures for children
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Genetic risk scores for predicting insulin resistance that were developed for adults are also tied to some cardiometabolic metrics in children and adolescents, according to study findings.
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Q&A: Surgeon General’s warning exposes public ‘knowledge gap’ of alcohol links to cancer
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There are approximately 100,000 alcohol-related cancer cases annually in the U.S. and 20,000 deaths due to alcohol-related cancer, according to an HHS press release.
US cases of MASLD projected to top 121 million by 2050 alongside 55% spike in MASH
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A new model has projected a substantial rise in the burden of metabolic dysfunction-associated steatotic liver disease in the U.S. by 2050, which could be minimized by effective preventive and management strategies, researchers wrote.
Q&A: Dry January trend ‘could be a wake-up call’ on risk for alcohol-related liver disease
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Dry January has become an increasingly popular trend in which people abstain from alcohol use for 1 month to reset their health after the holiday season. But, for some, it could be a wake-up call about their struggles with alcohol.
AGA urges antiviral prophylaxis for patients at high risk for hepatitis B reactivation
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In a new clinical practice guideline, the AGA provided evidence-based recommendations for either antiviral prophylaxis or continued surveillance to manage hepatitis B virus reactivation in patients receiving immunosuppressive therapy.
Chronic HBV treatment with xalnesiran plus immunomodulator confers highest HBsAg loss
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Treatment with xalnesiran, a small interfering RNA molecule, plus an immunomodulator resulted in hepatitis B surface antigen loss among adults with chronic HBV infection, according to a study published in The New England Journal of Medicine.
Q&A: Prenatal chemical exposure linked to liver injury in mothers, children 10 years later
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Exposure to environmental chemicals during pregnancy may increase the risk for liver injury and steatosis in children and mothers, which could be mitigated by higher folic acid supplementation, according to a study in Journal of Hepatology.
Q&A: First paired liver donation at Mayo a ‘significant first step’ to improving care
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The success of Mayo Clinic’s first paired living-donor liver transplantation may pave the way for expanded access and more “timely transplant” for patients in need, Timucin Taner, MD, PhD, told Healio.
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