VIDEO: Administering medication through the lymphatic system for rheumatoid arthritis

ByJeffrey A. Sparks, MD, MMSc

ByMarley V. Ghizzone

Fact checked byShenaz Bagha

SAN DIEGO — In this Healio video, Jeffrey A. Sparks, MD, MMSc, discusses results from a proof-of-concept study that assessed the efficacy of administering medication for rheumatoid arthritis into the peripheral lymphatic systems.

The findings were presented at ACR Convergence 2023.

“This was only 10 patients,” said Sparks, an associate professor of medicine at Harvard Medical School and an associate program director of the Rheumatology Fellowship, director of Immuno-Oncology and Autoimmunity and director of the Joint Biology Consortium Human Biosamples Core at Brigham and Women’s Hospital. “But this was not something I thought of before, is infusing drugs into the lymphatic system. [It] certainly needs bigger studies, so that’s sort of looking to the future about alternative methods of drug administration.”

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Sources/Disclosures

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Source:

Ross R, et al. Abstract 0838. Presented at: ACR Convergence 2023; Nov. 10-15, 2023; San Diego.

Disclosures: Sparks reports being supported by the Llura Gund Award funded by the Gordon and Llura Gund Foundation, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant numbers R01 AR080659, R01 AR077607, P30 AR070253, and P30 AR072577) and the R. Bruce and Joan M. Mickey Research Scholar Fund; receiving research support from Bristol Myers Squibb; and serving as a consultant for AbbVie, Amgen, Boehringer Ingelheim, Bristol Myers Squibb, Gilead Sciences Inc., Inova Diagnostics, Janssen, Optum, Pfizer, ReCor, Sobi and UCB.

Discoveries in Rheumatoid Arthritis

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VIDEO: Administering medication through the lymphatic system for rheumatoid arthritis

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