Rheumatoid Arthritis

TNF inhibitor use demonstrates no negative impact on survival among patients recently diagnosed with colorectal, lung or prostate cancer, according to data published in The Lancet Rheumatology.

Filgotinib, a Janus Kinase 1 inhibitor, remains well-tolerated for up to 8 years with consistent efficacy in patients with rheumatoid arthritis, according to data published in RMD Open.

Researchers’ understanding of the pathogenesis of rheumatoid arthritis has grown considerably in recent years, laying the groundwork that may inform a new generation of therapeutic targets and therapies.

For patients with rheumatoid arthritis and inadequate response to JAK inhibitors, cycling to another JAK inhibitor is a more effective option than switching to a biological disease-modifying antirheumatic drug, according to data.

Treatment with TNF inhibitors yielded no differences in outcomes vs. other antirheumatic therapies among U.S. veterans with rheumatoid arthritis-associated interstitial lung disease, according to data published in The Lancet Rheumatology.

The FDA has approved a third biosimilar for tocilizumab, called Avtozma, the second such biosimilar to be available in both intravenous and subcutaneous formulations, according to a press release.

While you wait for the groundhog to make his determination this weekend, take some time to buff up your knowledge of rheumatoid arthritis, a chronic autoimmune disease that affects about 1.5 million people in the United States.

In a large cohort of patients with autoimmune diseases, treatment with biologic disease-modifying antirheumatic drugs was associated with reduced incidence of Parkinson’s disease, data show.

Exposure to various air pollutants, such as PM2.5 and nitrogen oxides, increases the risk for several autoimmune diseases, including psoriasis, lupus and rheumatoid arthritis, according to data published in Scientific Reports.

Although sustained remission free of disease-modifying antirheumatic drugs “does not seem attainable” for patients with rheumatoid arthritis requiring biological DMARDs, it is possible for those who do not require them, according to data.