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February 12, 2025
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Flu at highest level in 15 years, CDC data show

Scleroderma News

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February 18, 2025
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FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion

FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion

The FDA has accepted an investigational new drug application for ALLO-329, an allogeneic chimeric antigen receptor T-cell therapy that may bypass lymphodepletion, paving the way for a phase 1 trial in lupus and other autoimmune diseases.

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February 12, 2025
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Pulmonary hypertension and the rheumatologist, part 1: A bit of background

Pulmonary hypertension and the rheumatologist, part 1: A bit of background

In this series, we dive into what rheumatologists should know about pulmonary hypertension, starting an interview with Joseph Parambil, MD, where we learn about the disease, when to suspect and how to work up!

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February 05, 2025
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Low-dose steroids fail to improve skin fibrosis in early diffuse systemic sclerosis

Low-dose steroids fail to improve skin fibrosis in early diffuse systemic sclerosis

Low doses of glucocorticoids added to immunosuppression yield no significant benefit for skin fibrosis in early diffuse cutaneous systemic sclerosis, according to data published in Arthritis Care & Research.

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IDN0225Flu_Graphic_01_WEB
February 12, 2025
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Flu at highest level in 15 years, CDC data show

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February 03, 2025
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Menopausal hormone therapy may increase risks for lupus, systemic sclerosis

Menopausal hormone therapy may increase risks for lupus, systemic sclerosis

The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of menopausal hormone therapy, according to data published in Rheumatology.

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January 17, 2025
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Medicare selects 15 drugs for second round of price negotiations, including semaglutide

Medicare selects 15 drugs for second round of price negotiations, including semaglutide

CMS has selected 15 new drugs for the next round of Medicare Part D price negotiations, according to a press release from HHS.

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January 16, 2025
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Frailty in systemic sclerosis increases mortality risk nearly 10 times

Frailty in systemic sclerosis increases mortality risk nearly 10 times

Frailty among patients with systemic sclerosis significantly increases the risk for mortality by nearly 10-fold, but shows the potential to improve over time, according to data published in Clinical Rheumatology.

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December 31, 2024
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CAR T therapy for autoimmune disease exploded in 2024. Here’s what you may have missed

CAR T therapy for autoimmune disease exploded in 2024. Here’s what you may have missed

After first generating excitement in late 2022, this year was a bonanza for news about chimeric antigen receptor T-cell therapies for autoimmune rheumatic diseases.

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December 18, 2024
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CAR T therapy shows ‘no major hematotoxicites’ in autoimmune disease phase 1/2 study

CAR T therapy shows ‘no major hematotoxicites’ in autoimmune disease phase 1/2 study

WASHINGTON — A phase 1/2 study of CD19 chimeric antigen receptor T-cell therapy in lupus and other autoimmune diseases demonstrated significant response with minimal toxicities, according to data presented at ACR Convergence 2024.

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December 17, 2024
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CD19 CAR-T therapy yields long-term benefits in lupus, myositis, systemic sclerosis

CD19 CAR-T therapy yields long-term benefits in lupus, myositis, systemic sclerosis

WASHINGTON — CD19 chimeric antigen receptor T-cell therapy led to remission, or ceased disease progression, over a period of up to 15 months in 35 patients with lupus, myositis and systemic sclerosis, according to data.

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December 06, 2024
3 min read
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New EULAR systemic sclerosis recommendations illuminate a ‘significantly changed’ field

New EULAR systemic sclerosis recommendations illuminate a ‘significantly changed’ field

EULAR has released new recommendations on the treatment of systemic sclerosis, advancing new treatments and updated approaches to key manifestations such as skin and lung fibrosis.

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