Log in or Sign up for Free to view tailored content for your specialty!
Scleroderma News

‘There is a whole other world out there’: Beyond CAR-T therapies for autoimmune diseases
Although chimeric antigen receptor T-cell therapy has raised hopes for long-term remission in autoimmune disease, it has several limitations that may be overcome instead through bispecific T-cell-engaging antibodies, according to a speaker.
FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion

The FDA has accepted an investigational new drug application for ALLO-329, an allogeneic chimeric antigen receptor T-cell therapy that may bypass lymphodepletion, paving the way for a phase 1 trial in lupus and other autoimmune diseases.
Pulmonary hypertension and the rheumatologist, part 1: A bit of background

In this series, we dive into what rheumatologists should know about pulmonary hypertension, starting an interview with Joseph Parambil, MD, where we learn about the disease, when to suspect and how to work up!
Log in or Sign up for Free to view tailored content for your specialty!
Low-dose steroids fail to improve skin fibrosis in early diffuse systemic sclerosis

Low doses of glucocorticoids added to immunosuppression yield no significant benefit for skin fibrosis in early diffuse cutaneous systemic sclerosis, according to data published in Arthritis Care & Research.
Menopausal hormone therapy may increase risks for lupus, systemic sclerosis

The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of menopausal hormone therapy, according to data published in Rheumatology.
Medicare selects 15 drugs for second round of price negotiations, including semaglutide

CMS has selected 15 new drugs for the next round of Medicare Part D price negotiations, according to a press release from HHS.
Frailty in systemic sclerosis increases mortality risk nearly 10 times

Frailty among patients with systemic sclerosis significantly increases the risk for mortality by nearly 10-fold, but shows the potential to improve over time, according to data published in Clinical Rheumatology.
CAR T therapy for autoimmune disease exploded in 2024. Here’s what you may have missed

After first generating excitement in late 2022, this year was a bonanza for news about chimeric antigen receptor T-cell therapies for autoimmune rheumatic diseases.
CAR T therapy shows ‘no major hematotoxicites’ in autoimmune disease phase 1/2 study

WASHINGTON — A phase 1/2 study of CD19 chimeric antigen receptor T-cell therapy in lupus and other autoimmune diseases demonstrated significant response with minimal toxicities, according to data presented at ACR Convergence 2024.
CD19 CAR-T therapy yields long-term benefits in lupus, myositis, systemic sclerosis

WASHINGTON — CD19 chimeric antigen receptor T-cell therapy led to remission, or ceased disease progression, over a period of up to 15 months in 35 patients with lupus, myositis and systemic sclerosis, according to data.
-
Headline News
Limiting daily TV time to 1 hour may reduce risk for atherosclerotic heart disease
March 12, 20253 min read -
Headline News
King Holmes, ‘giant’ of medicine and STI research, dies at 87
March 11, 20252 min read -
Headline News
Pregnancy may bring about persistent changes to the eye
March 10, 20252 min read
-
Headline News
Limiting daily TV time to 1 hour may reduce risk for atherosclerotic heart disease
March 12, 20253 min read -
Headline News
King Holmes, ‘giant’ of medicine and STI research, dies at 87
March 11, 20252 min read -
Headline News
Pregnancy may bring about persistent changes to the eye
March 10, 20252 min read