Sjögren’s Syndrome News

Despite being the second-most common rheumatic autoimmune disease in the United States, Sjögren’s syndrome remains under-recognized, with patients often waiting 3 years for a proper diagnosis, according to the Sjögren’s Foundation.

It has been at least 2 years since the first cohort of patients with lupus underwent chimeric antigen receptor T-cell treatment, and, at least so far, for every one of them, each new dawn represents another day spent in full remission.

Nightmares and hallucinations may occur at any stage of disease course in patients with systemic lupus erythematosus, according to recent findings.

Patients with Sjögren’s disease treated with nipocalimab, a novel neonatal Fc receptor blocker, demonstrate significant improvement vs. those who receive placebo at week 24, according to data presented at the EULAR 2024 Congress.

Most pediatric patients with Sjögren’s disease displayed an interferon signature in their blood and parotid gland tissue, which could help confirm diagnoses and shorten treatment delays, according to data presented at EULAR 2024 Congress.

Sjögren’s disease is one of the most common autoimmune diseases but one of the least known, so to raise awareness of the condition, April is designated Sjögren’s Awareness Month.

This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin.

Patients with prior sinusitis demonstrate an increased risk for many rheumatic diseases, including antiphospholipid syndrome, Sjögren’s disease and seronegative rheumatoid arthritis, according to data published in RMD Open.

Pregnant patients with lupus or antiphospholipid syndrome have a higher risk for preterm birth, although immune-mediated inflammatory diseases in general are “only weakly associated” with adverse pregnancy outcomes, according to data.