Antiphospholipid Syndrome News

Pregnant patients with lupus or antiphospholipid syndrome have a higher risk for preterm birth, although immune-mediated inflammatory diseases in general are “only weakly associated” with adverse pregnancy outcomes, according to data.

SAN DIEGO — Patients with systemic lupus erythematosus who are positive for antiphospholipid antibodies have a greater risk for future atherosclerotic cardiovascular disease, according to data presented at ACR Convergence 2023.

Updated classification criteria for antiphospholipid syndrome require patients display at least one positive antiphospholipid antibody test within 3 years of a linked disease manifestation, according to new guidance from the ACR and EULAR.

SAN DIEGO — Pregnant patients with concomitant systemic lupus erythematosus and antiphospholipid syndrome have an 18-fold increased risk for cardiovascular events vs. healthy pregnant controls, said a speaker at ACR Convergence 2023.

Following last year’s U.S. Supreme Court’s decision overturning federal abortion protections, rheumatologists must change their practice with regard managing patients’ reproductive health, said presenter at the 2023 AWIR annual conference.

Upcoming American College of Rheumatology and EULAR joint classification criteria for antiphospholipid syndrome will “create a homogenous patient population” to increase research, according to a presenter at the 2023 AWIR annual conference.

Anticardiolipin IgA and a2GPI IgA positivity, together at a single time point, indicate an increased risk for future atherosclerotic cardiovascular disease events, according to data published in JAMA Network Open.

The next therapeutic innovation in complement biology therapies for rheumatic diseases may involve inhibiting the alternative complement pathway, according to a speaker at the Biologic Therapies Summit.

PHILADELPHIA — Upcoming T-cell therapies may treat antiphospholipid syndrome and other autoimmune diseases without compromising a patient’s defenses against infection, according to data presented at ACR Convergence 2022.