Top in endocrinology: Safety of semaglutide; impact of endocrine-disrupting chemicals
Click Here to Manage Email Alerts
Adults using semaglutide for type 2 diabetes or obesity treatment are at a lower risk for suicidal ideation than adults using non-GLP-1 receptor agonists, according to recent findings.
The study was conducted in response to anecdotal reports of suicidal thoughts among patients using Wegovy and Ozempic (semaglutide, Novo Nordisk).
“Our findings, while they require replication, do not support concerns that semaglutide might increase suicidal ideations in patients being treated for their obesity or diabetes compared to other medications used for these indications,” Nora Volkow, MD, director of the National Institute on Drug Abuse at the NIH, told Healio.
It was the top story in endocrinology last week.
Another top story was about the disease burden attributed to endocrine-disrupting chemicals in plastics, which was estimated to cost $249 billion in 2018, or 1.22% of the nation’s gross domestic product.
Read these and more top stories in endocrinology below:
Semaglutide linked to lower suicidal ideation risk than other obesity, diabetes drugs
Adults receiving semaglutide as a type 2 diabetes or obesity medication have a lower risk for suicidal ideation than those who are using a drug that is not a GLP-1 receptor agonist, according to findings published in Nature Medicine. Read more.
Endocrine-disrupting chemicals in plastics add $249 billion to US health care costs
Exposure to plastics containing endocrine-disrupting chemicals added an estimated $249 billion to health care costs in the United States in 2018, according to study data. Read more.
Combination insulin icodec and semaglutide cuts HbA1c and body weight in type 2 diabetes
Once-weekly combination therapy of basal insulin icodec and semaglutide was noninferior to insulin glargine plus insulin aspart for lowering HbA1c among adults with type 2 diabetes, according to topline results from a phase 3a trial. Read more.
Exposure to endocrine-disrupting chemicals may lower odds for achieving pregnancy
Exposure to endocrine-disrupting phthalates may reduce women’s fecundability, or odds of becoming pregnancy during a menstrual cycle, according to findings published in Environmental Health Perspectives. Read more.
Radiofrequency ablation eliminates tumor for most adults with low-risk thyroid cancer
More than 95% of adults with low-risk papillary thyroid cancer were disease-free after radiofrequency ablation, according to findings from a single-center study published in Thyroid. Read more.