Pharmacology News

SAN FRANCISCO — New data suggest that lenacapavir delivered just once per year could be as effective for HIV prevention as the twice-yearly injections already under review by the FDA.

An analysis of recent drug use in the United States revealed unexpected trends in substances being used in tandem with fentanyl, according to an expert.

An antibiotic stewardship intervention at urgent care centers was associated with lower rates of inappropriate prescribing for bronchitis and viral upper respiratory infections, although active clinician engagement is necessary, researchers found.

The American Society of Anesthesiologists released new guidance on the safe use of ketamine for nonanesthesia purposes, such as the treatment of mental health disorders, according to an organization press release.

I routinely see prescribers avoid prescribing cephalosporin antibiotics for patients with a penicillin allergy.

Paxlovid may not decrease the risk for hospitalization or death in older adults vaccinated against COVID-19 as much as previously thought, according to research published in JAMA.

Less than 5% of hospitalized adults with type 2 diabetes received an SGLT2 inhibitor or GLP-1 before being discharged, according to data from a cohort study published in the Journal of Diabetes and Its Complications.

Antidepressants were more effective than placebo in reducing anxiety symptoms among adults with moderate to severe generalized anxiety disorder, according to a review published in Cochrane Database of Systematic Reviews.

NSAIDs “provide the greatest benefit and least harm” for treating acute pain in children compared with ketamine and opioids, according to findings from a systematic review and meta-analysis published in JAMA Pediatrics.