Pharmacology News

Antidepressants were more effective than placebo in reducing anxiety symptoms among adults with moderate to severe generalized anxiety disorder, according to a review published in Cochrane Database of Systematic Reviews.

NSAIDs “provide the greatest benefit and least harm” for treating acute pain in children compared with ketamine and opioids, according to findings from a systematic review and meta-analysis published in JAMA Pediatrics.

In a systematic review and meta-analysis of trials of non-vitamin K oral anticoagulants vs. single antiplatelet therapy, rivaroxaban was associated with higher rates of major bleeding compared with low-dose aspirin, researchers reported.

The FDA approved 16 psychiatric drugs over the last decade, most of which shared similar mechanisms of action with previously developed drugs, according to data in a research latter published in JAMA Network Open.

The FDA has approved Journavx 50 mg oral tablets for the treatment of moderate to severe acute pain in adults, according to a press release.

Pharmacy benefit managers overcharged for specialty generic medications — in many cases by hundreds and thousands of percent — for billions in profits, according to a report from the Federal Trade Commission, or FTC.

Participants with metabolic syndrome who received 1,700 mg metformin daily with or without a Mediterranean diet intervention had reduced incidence of diabetes compared with placebo, according to findings published in Diabetes Care.

The volume of those who received medications for opioid use disorder at federally qualified health centers more than doubled over a recent 6-year span, results from a cross-sectional study showed.

Using a novel approach accounting for prescriber preference, researchers found that longer durations of antibiotic therapy was not associated with greater risk of harm or benefit compared to a shorter duration.