Rheumatology News

Duloxetine, milnacipran and pregabalin can yield significant pain relief over at least 12 weeks for approximately one out of 10 adults with fibromyalgia, according to an analysis of Cochrane reviews published in Rheumatology.

Patients aged 65 years and older who use acetaminophen demonstrate greater risks for serious complications, including hypertension, chronic kidney disease and gastrointestinal bleeding, noted a study published in Arthritis Care & Research.

Tacrolimus appears to have “synergistic” interactions with mycophenolate mofetil and cyclophosphamide for the treatment of renal involvement in systemic lupus erythematosus, according to observational data published in BMC Rheumatology.

Colchicine for gout flare prophylaxis reduces the risk for cardiovascular events among patients initiating urate-lowering therapy, according to data published in The Lancet Rheumatology.

For patients with psoriatic arthritis, switching directly from adalimumab to tofacitinib with no washout period presents no increased safety risks, according to data published in Arthritis Research & Therapy.

A non-invasive diagnostic model, based partially on saliva samples, distinguished between patients with and without Sjögren’s disease with high sensitivity and specificity, according to data published in Arthritis Research & Therapy.

Women with axial spondyloarthritis face longer diagnostic delays and greater disease burden than men despite higher rates of treatment and healthy behaviors, according to data published in International Journal of Rheumatic Diseases.

A once-daily dose of ivarmacitinib reduced disease activity and improved function among patients with rheumatoid arthritis through 52 weeks, according to phase 3 trial results published in Annals of the Rheumatic Diseases.

Patients’ perception of their illness and coping styles may play a role in whether hand osteoarthritis pain improves or deteriorates over the long term, according to data published in Arthritis Care & Research.