Top in endocrinology: Calorie restriction intervention; bariatric surgery vs. GLP-1 drugs

A calorie-restricted intermittent fasting intervention demonstrated clinical efficacy in achieving type 2 diabetes remission, a recent study showed.

Participants who adhered to the intervention, which included 5 days of intermittent fasting followed by 10 days of eating ad libitum, had greater reductions in fasting blood glucose and HbA1c than those who adhered to an ad libitum diet alone. It was the top story in endocrinology last week.

Another top story was about a study that compared the benefits of bariatric surgery vs. GLP-1 receptor agonist therapy in adults with obesity. Researchers found that bariatric surgery conferred greater weight and BMI reductions, but both modalities had similar effects on HbA1c.

Read these and more top stories in endocrinology below:

Nearly half of adults with type 2 diabetes saw remission with calorie restriction, timing

Nearly half of a cohort of adults with type 2 diabetes participating in a calorie-restricted intermittent fasting intervention achieved diabetes remission, according to findings from a randomized controlled trial in China. Read more.

More weight loss but similar HbA1c reduction seen with bariatric surgery vs. GLP-1 drugs

Among adults with obesity, bariatric surgery conferred greater weight and BMI reductions than GLP-1 receptor agonist therapy, but effects on HbA1c were similar between the two modalities, researchers reported. Read more.

COVID-19 infection increases risk for incident diabetes by 64%

The risk for incident type 1 or type 2 diabetes increases after a COVID-19 infection, according to findings from a systematic review and meta-analysis published in Metabolism: Clinical and Experimental. Read more.

Nearly 25% of children with type 2 diabetes do not have obesity

Obesity was not a universal phenotype among children with type 2 diabetes, despite being an important risk factor, according to a systematic review and meta-analysis published in JAMA Network Open. Read more.

No impact of time-restricted eating seen on sex steroids for women with obesity

Short-term time-restricted eating resulted in no changes in sex steroid levels but was associated with a decrease in dehydroepiandrosterone for premenopausal and postmenopausal women with obesity, according to study data. Read more.