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August 19, 2022
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Top in GI: Viruses implicated in hepatitis surge; NASH is driving liver cancer deaths

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A combination of viruses has been linked to an unexplained surge of severe hepatitis in children.

Researchers found that coinfection with adenovirus type F41 — a common virus in children — and adeno-associated virus 2 and a family of herpes viruses could be responsible for the outbreak. It was the top story in gastroenterology last week.

MRI scan of liver
Research showed that nonalcoholic steatohepatitis is driving an increase in liver cancer mortality in the Americas. Source: Adobe Stock

Another top story focused on a study that showed nonalcoholic steatohepatitis (NASH) is behind an increase in liver cancer mortality.

Read these and more top stories in gastroenterology below:

Expert: Virus pairing creates ‘perfect storm’ for unexplained hepatitis surge in children

New research has linked the incidence of unexplained hepatitis in pediatric patients to a pair of viruses — adenovirus type F41 and adeno-associated virus 2 — as well as potential markers of genetic mutation. Read more.

NASH ‘fastest growing cause’ of liver cancer death worldwide

Despite global declines in liver cancer mortality attributed to hepatitis B and C, liver cancer mortality rose sharply in the Americas, driven by an increase in nonalcoholic steatohepatitis, according to data published in Cell Metabolism. Read more.

Patients with severe childhood-onset IBD earned ‘markedly’ less in early adulthood

Individuals with severe childhood-onset inflammatory bowel disease, who underwent surgery or long-term inpatient care, had 16% lower occupational earnings from age 20 to 30 years compared with the general population, according to research. Read more.

Gastroparesis Awareness Month: Guideline updates, diabetic GP, G-POEM

Healio handpicked a series of stories on gastroparesis to raise awareness and increase education during Gastroparesis Awareness Month. Read more.

Heavy alcohol use, gene variant heighten risk for HCC, mortality in HBV-related cirrhosis

Patients with cirrhosis who have hepatitis B virus infection and a history of heavy alcohol use are at higher risk for hepatocellular carcinoma and mortality, according to a study published in JAMA Network Open. Read more.