Hepatitis
Larsucosterol flops on clinical benefit in phase 2b alcohol-associated hepatitis trial
The AHFIRM trial did not demonstrate a beneficial effect of larsucosterol on 90-day mortality or the need for liver transplant among patients with severe alcohol-associated hepatitis, or AH, according to a study published in NEJM Evidence.
Hispanic patients with alcohol use disorder face greater odds for hepatitis, cirrhosis
Hispanic patients hospitalized for alcohol use disorder were more likely to develop alcohol-associated hepatitis, decompensated cirrhosis and related complications compared with non-Hispanic white patients, according to published data.
Man presents with right-sided headaches, ocular pain and vesicular rash
A 64-year-old man presented to the emergency department at Lahey Hospital with a 6-day history of right-sided headaches, right ocular pain and vesicular rash.
Organ network to remove race, hepatitis C coefficients for evaluating organ function
The Organ Procurement and Transplantation Network has removed two variables – whether a potential organ donor is African American or Black or has tested positive for the hepatitis C virus – from methods to evaluate deceased donor organs.
CDC: Learning ‘ABCs of viral hepatitis’ may help boost early testing, vaccination
During Hepatitis Awareness Month, the CDC and allied public health organizations launched educational campaigns to raise awareness of viral hepatitis, deflate stigma around the infection and encourage early testing and vaccination.
FDA rejects expanded use of Dynavax’s four-dose hepatitis B vaccine for hemodialysis
The FDA has declined to approve Dynavax’s supplemental biologics license application for the expanded use of its four-dose hepatitis B vaccine regimen in adult patients on hemodialysis, according to a manufacturer’s press release.
Q&A: ‘False sense of safety’ contributes to rise in STDs after menopause
In the past decade, STDs have increased among women aged at least 55 years, highlighting the importance of discussing sexual partners, sexual history and condom use with all patients, regardless of age.
VIDEO: 7 general principles ‘help to frame’ routine preventive vaccination in IBD
In a Healio video exclusive, Gil Y. Melmed, MD, MS, outlines seven principles supported by literature that “help to frame” how providers should address routine preventive vaccination for patients with inflammatory bowel disease.
Pre-pandemic ED visits for alcohol-related hepatitis rose by 4.4% among younger patients
An analysis of ED utilization from 2016 to 2019 revealed an increase in visits for alcohol-associated hepatitis, particularly among patients aged 25 to 44 years, as well as an increase in disease severity.
FDA grants fast track status to investigational bepirovirsen for chronic hepatitis B
The FDA has granted fast track designation to GSK’s bepirovirsen, a triple action investigational antisense oligonucleotide, for the treatment of chronic hepatitis B virus infection, according to a manufacturer release.