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May 29, 2022
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Top in cardiology: Metformin use in prediabetes; sleep apnea and CVD

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In a recent study, researchers found no between-group differences in myocardial infarction, stroke or cardiovascular death among patients with prediabetes who received metformin, a lifestyle intervention or placebo.

A review of the data was the top story in cardiology last week.

pharmacy container of metformin tablets Metformin Adobe 2019
Source: Adobe Stock

Another top story explored efforts to improve access to sleep apnea care through cardiology practice accreditation. Raman Malhotra, MD, FAASM, the president of the American Academy of Sleep Medicine, said that cardiologists are “in a unique position” to improve the screening and diagnosis of obstructive sleep apnea, which is common among patients with CVD.

Read these and more top stories in cardiology below:

No CV benefit with metformin, lifestyle intervention, despite diabetes prevention

In adults with prediabetes, metformin and lifestyle interventions decreased the likelihood of type 2 diabetes development but did not reduce risk for major adverse cardiovascular events compared with placebo during 21 years of follow-up, data show. Read more.

Improving access to sleep apnea care through cardiology practice accreditation

Patients with CVD are 40% to 80% more likely to have comorbid obstructive sleep apnea, which in severe cases can cause them to stop breathing hundreds of times a night. Read more.

Very high HDL ‘red flag’ for all-cause, CV death risk in adults with CAD

In adults with CAD, those with HDL of 80 mg/dL or greater are nearly twice as likely to die of any cause compared with those with HDL between 40 mg/dL and 60 mg/dL, according to an analysis of two large biobank databases. Read more.

Polygenic component associated with HCM risk, offering prediction tool

Rare and common genetic variants contribute substantially to susceptibility to hypertrophic cardiomyopathy in the general population and can help improve risk prediction beyond clinical factors, researchers reported. Read more.

Low income tied to mortality risk after STEMI hospitalization

Patients with low household income who presented with STEMI faced greater risk for inpatient mortality, longer hospital stay and need for invasive mechanical ventilation vs. patients with higher income, data show. Read more.