Metformin

A randomized controlled trial demonstrated a significantly reduced incidence of type 2 diabetes among individuals with metabolic syndrome who received daily metformin with or without a Mediterranean diet intervention.

Participants with metabolic syndrome who received 1,700 mg metformin daily with or without a Mediterranean diet intervention had reduced incidence of diabetes compared with placebo, according to findings published in Diabetes Care.

Treatment with metformin plus glyburide was not noninferior to insulin alone in preventing large for gestational age infants born from pregnant women with gestational diabetes, according to trial results published in JAMA.

Metformin may have potential in preventing nonmelanoma skin cancer, including in most populations with skin of color, according to a study.

Patients with type 2 diabetes uncontrolled by metformin who received pioglitazone and insulin demonstrated increased risk for ischemic heart disease, according to findings published in the Journal of Diabetes and Its Complications.

Healio has compiled the most-read news in pulmonology posted in November.

Among adults with asthma and type 2 diabetes, there was a link between metformin use and fewer asthma attacks, according to results published in JAMA Internal Medicine.

BOSTON — Among adults with COPD, the odds for exacerbations and hospitalizations were elevated in patients who did not use vs. did use the diabetes medication metformin, according to an abstract presented at the CHEST Annual Meeting.

Adults with type 2 diabetes using metformin before or during a SARS-CoV-2 infection may have a lower risk for long COVID than those using other diabetes medications, according to findings published in Diabetes Care.

Down regulation of fibrotic processes and upregulation of keratinocyte proliferation was associated with low-dose metformin in patients with central centrifugal cicatricial alopecia, or CCCA, according to a study.