Metformin

Adults with type 2 diabetes using metformin before or during a SARS-CoV-2 infection may have a lower risk for long COVID than those using other diabetes medications, according to findings published in Diabetes Care.

Down regulation of fibrotic processes and upregulation of keratinocyte proliferation was associated with low-dose metformin in patients with central centrifugal cicatricial alopecia, or CCCA, according to a study.

Metformin may protect against the progression of adverse renal and cardiovascular outcomes in patients systemic lupus erythematosus, including lupus nephritis and infarction, according to data published in ACR Open Rheumatology.

People with type 2 diabetes who use a GLP-1 receptor agonist have a lower risk for 10 types of obesity-associated cancer compared with those who use insulin, according to data published in JAMA Network Open.

Maternal and paternal metformin use during conception did not increase the risk for adverse pregnancy outcomes, two studies in Annals of Internal Medicine showed.

Metformin exposure during pregnancy was not associated with adverse childhood neurodevelopmental outcomes up to age 14 years, according to a systematic review and meta-analysis published in the American Journal of Obstetrics and Gynecology.

Feeding children peanut products from infancy to age 5 years reduced the prevalence of peanut allergy into adolescence, according to recent data.

SAN DIEGO — Children with asthma who used metformin experienced decreases in asthma-related hospitalizations and oral steroid use, according to an abstract presented at the American Thoracic Society International Conference.