Transplantation News

Patients who underwent liver transplantation vs. alternative therapy for unresectable colorectal liver metastasis had higher progression-free and overall survival, as well as lower rates of recurrence, researchers reported in JAMA Surgery.

A continuous risk score accurately predicted waitlist dropout and post-liver transplantation outcomes in patients with hepatocellular carcinoma, even over the course of several UNOS policy changes, researchers reported.

The new United Network for Organ Sharing liver allocation policy has resulted in a significant increase in the number and cost of liver imports, with greater costs incurred by low-income states and underserved areas, according to analysis.

Interim results from a global, multicenter study demonstrated the benefit of liver transplantation among patients with acute-on-chronic liver failure grades 2 and 3 and suggest that current allocation systems are inadequate.

Recurrence of hepatic encephalopathy was lower among patients with cirrhosis and hepatic encephalopathy who received oral capsule or enema fecal microbiota transplant vs. placebo, according to research from EASL Congress.

WASHINGTON — In a Healio video exclusive, Saqr Alsakarneh, MD, MSc, describes “significant disparities” in race, ethnicity and sex among participants enrolled clinical trials for liver transplantation in the U.S.

Recipients of livers recovered by normothermic regional perfusion vs. standard super rapid recovery experienced lower rates of ischemic cholangiopathy and biliary complications, with comparable patient and graft survival, data showed.

A “vast majority” of liver transplant centers use stigmatizing language, such as “alcoholic” or “alcohol abuse,” when describing patients with alcohol use disorder and alcohol-associated liver disease on their websites, researchers reported.

Chronic liver disease is the ninth leading cause of death in the United States, independent of liver cancer. According to the CDC, only 1.8% of adult Americans have a diagnosis of chronic liver disease, which translates to 4.5 million people.

Older adult patients with acute-on-chronic liver failure had significantly higher waitlist mortality but “acceptable” 1-year survival after liver transplantation, according to data in Clinical Gastroenterology and Hepatology.