VIDEO: Linaclotide yields early reduction in IBS with constipation symptoms
LAS VEGAS – Darren M. Brenner, MD, reported at the ACG Annual Scientific Meeting that linaclotide reduces abdominal pain and other symptoms of irritable bowel syndrome with constipation within 4 weeks of treatment.
“Importantly, if you allow the patient to continue to take the medication for more than 4 weeks, you may see improvements in 10% to 15% of individuals after that with respect to their abdominal or bowel symptoms,” Brenner said.
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Brenner DM, et al. Time to relief of key abdominal and bowel symptoms of irritable bowel syndrome with constipation: A post-hoc analysis of randomized controlled trials of linaclotide. Presented at: ACG Scientific Annual Meeting; Oct. 22-27, 2021; Las Vegas (hybrid meeting).
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