7 recent reports on endoscopy
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Healio Gastroenterology and Liver Disease presents the following reports on the most recent research in endoscopy.
These reports review some of the most recent developments on colonoscopy preparations, bariatric endoscopy and quality improvement in the world of endoscopy.
FDA clears first single-use, disposable duodenoscope
The FDA authorized marketing of Boston Scientific’s EXALT Model D Single-Use Duodenoscope, the first fully disposable version of the device that allows physicians to view the upper gastrointestinal tract, according to an FDA news release.
The EXALT is designed for use on a single patient to avoid the need for cleaning and sterilization required for devices intended to be reused for multiple patients, which should reduce the potential for spreading infection among patients, according to the FDA. READ MORE
Endoscopic sleeve gastroplasty safe in children, adolescents
Endoscopic sleeve gastroplasty was found to be safe and effective in children and adolescents with obesity, according to data published in the American Journal of Gastroenterology.
“We incorporated [endoscopic sleeve gastroplasty] into our standardized pediatric bariatric clinical pathway with a few modifications,” Aayed Alqahtani, MD, FRCSC, FACS, an associate professor of surgery at King Saud University in Riyadh, Saudi Arabia, and colleagues wrote. “Patients were offered enrollment in our pediatric weight loss program if their BMI was higher than the 95th percentile for age and sex.” READ MORE
ColonaryConcepts targets phase 3 trial for edible colonoscopy prep
A novel colonoscopy preparation designed to be more palatable for patients could be headed to a phase 3 trial next year after ColonaryConcepts announced it has reacquired its rights.
Originally sold to Sebela Pharmaceuticals in 2017, EC Prep integrates active colonoscopy prep ingredients into “nutritionally balanced bars” and beverages, according to a press release. READ MORE
GIQuIC registry surpasses 10 million colonoscopies
The registry for The GI Quality Improvement Consortium, known as GIQuIC, now comprises reported data from more than 10 million colonoscopy procedures, the nonprofit group announced.
Established in 2010 as a partnership between the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy, GIQuIC serves as a clinical benchmarking tool that tracks more than a dozen colonoscopy quality measures, like adenoma detection rate, bowel prep assessment and adherence to appropriate screening intervals. READ MORE
Low-volume bowel prep still effective, but better tolerated
Low-volume, split-dose bowel preparations were just as effective as high-volume preps with the added benefit of being better tolerated by patients, according to the results of a metanalysis.
“Suboptimal patient compliance and acceptability have been attributed to the large volume of bowel preparation to be administered, affecting patient experience and willingness to repeat the procedure,” Marco Spadaccini, MD, of the digestive endoscopy unit at Humanitas Research Hospital in Italy, and colleagues wrote. “When considering patient experience as a relevant outcome of bowel preparation, low-volume [polyethylene glycol (PEG)] and non-PEG split regimens appear to be an attractive alternative, due to a substantial reduction in the volume to be administered.” READ MORE
POEM more effective than previous estimates for achalasia
Peroral endoscopic myotomy is highly safe and effective for at least 1 year for the treatment of achalasia and outperformed previous efficacy estimates, according to study results.
Haruhiro Inoue, MD, PhD, of the digestive disease center at Showa University Koto-Toyosu Hospital in Japan, and colleagues wrote that previous studies have found that POEM has a therapeutic efficacy — defined as an Eckardt score no greater than 3 — between 82% and 95% after 1 year. READ MORE
AI bests non-expert endoscopists in Barrett’s neoplasia detection
Researchers developed a deep-learning, computer aided system that detected neoplasia in patients with Barrett’s esophagus at a better rate than nonspecialized endoscopists, according to study results.
J.J. Bergman, MD, PhD, and colleagues wrote that technological improvements have aided the detection of neoplasia, but detection failure is still not uncommon, particularly among some groups of clinicians. READ MORE