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‘U’ stitch endoscopic sleeve gastroplasty safe, effective for obesity
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Using a uniform “U” stitch suture pattern across all endoscopic sleeve gastroplasty procedures could provide a safe and effective option for the management of obesity and overweight, according to study results.
Christopher C. Thompson, MD, MSc, FASGE, director of endoscopy at Brigham and Women’s Hospital, and colleagues wrote in Gastrointestinal Endoscopy that as the procedure has evolved, so has the kind of suture used, leading to a lack of data. They wrote that their study is the first to focus exclusively on the “U” stitch.
“A limitation of the prior literature has been this technical heterogeneity as evidenced by multiple techniques reported across the literature, as well as, within most individual publications,” they wrote. “The ‘U’ stitch has recently been adopted by many centers; however, there are limited data on this in the published literature.”
Researchers analyzed data collected from seven centers comprising 193 patients with obesity or overweight who underwent endoscopic sleeve gastroplasty. They assessed the procedure’s efficacy in terms of absolute weight loss (AWL), percentage of total weight lost (%TWL), change in BMI and percentage of excess weight lost (%EWL) at 6 and 12 months in overweight and obese class I, II and III. They also assessed immediate and delayed adverse events.
At 6 months follow-up, all groups had a TWL greater than 10% and a %EWL greater than 25%. The average %TWL was 14.25% ± 5.26 at 6 months and 15.06% ± 5.22 at one year, while the average %EWL was 56.15% ± 22.93 and 59.41% ± 25.69 in those respective time frames.
Researchers found that the %TWL at one year was 8.91% ± 0.3 for overweight, 13.92% ± 5.76 for obese class I, 16.22% ± 7.69 for obese class II, and 19.01% ± 0.95 for obese class III. Additionally, %EWL was 56.21% ± 2 in the overweight group, 62.03% ± 27.63 for obese class I, 54.13% ± 23.46 for obese class II, and 46.78% ± 2.43 for obese class III.
In their safety assessment, researchers found that two patients experienced severe adverse events, specifically two perigastric collections that required surgery.
Disclosures: Healio Gastroenterology and Liver Disease could not confirm the authors’ relevant financial disclosures prior to publication.
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