January 04, 2019
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Top 5 gastroenterology articles posted in December

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Healio Gastroenterology and Liver Disease has compiled a list of the top five stories posted in December.

Our readers were most interested in antidepressant use in IBD, as well as supervised pelvic floor muscle training for fecal incontinence and FDA’s approval of Motegrity.

Antidepressants could impact disease course in IBD

Antidepressants could be a beneficial therapy for patients with inflammatory bowel disease for symptoms beyond anxiety and depression, according to research published in Inflammatory Bowel Diseases.

Investigators found that those who used antidepressants after diagnosis had a lower incidence rate of disease activity compared with non-users in both CD (IRR = 0.75; 95% CI, 0.68–0.82) and UC (IRR = 0.9; 95% CI, 0.84–0.95). READ MORE.

FDA approves Motegrity for chronic idiopathic constipation

The FDA has approved Motegrity for the treatment of adults with chronic idiopathic constipation, according to a company press release.

“As a gastroenterologist, it’s important for me to help patients with CIC find a treatment that works well for them,” Brooks Cash, MD, chief of the Division of Gastroenterology, Hepatology, and Nutrition at the University of Texas Health Science Center at Houston, said in the release. “It’s exciting to be able to now offer my patients a new treatment option that addresses colonic peristalsis.” READ MORE.

6 common mistakes when treating patients with ulcerative colitis

ORLANDO — When a patient with ulcerative colitis is sick enough to be admitted to the hospital, the stakes can be incredibly high. In a presentation at Advances in IBD 2018, Corey Siegel, MD, of the Dartmouth-Hitchcock Medical Center, said there is little room for mistakes with these patients.

For his talk, Siegel sought the help of national and international experts in gastroenterology and surgery to find some of the most common mistakes physicians make when treating patients with severe UC. READ MORE.

Pelvic floor muscle training with biofeedback helps improve symptoms of fecal incontinence

Patients who underwent supervised pelvic floor muscle training with biofeedback were five times more likely to experience improvements in fecal incontinence symptoms, according to research published in Clinical Gastroenterology and Hepatology.

Anja Ussing, MSc, of the department of physiotherapy and occupational therapy at Copenhagen University Hospital, and colleagues wrote that even though pelvic floor muscle training (PFMT) is a component of first-line therapy for fecal incontinence, research on its effect has been limited. READ MORE.

WATS3D helps increase detection of esophageal dysplasia, Barrett’s

Adding Wide Area Transepithelial Sampling with 3D Tissue Analysis to standard targeted and random forceps biopsy helped increase detection of esophageal dysplasia, as well as Barrett’s esophagus, according to research published in Diseases of the Esophagus.

“With the results of this and other published studies, the evidence is overwhelming that we should be using WATS3D [CDx Diagnostics] along with forceps biopsies to evaluate all of our BE patients,” Michael S. Smith, MD, MBA, chief of gastroenterology and hepatology as Mount Sinai West and Mount Sinai St. Luke’s Hospital, said in a press release. READ MORE.