Detection rates better when EndoRings colonoscopy preceded standard colonoscopy

CHICAGO — Patients who underwent an EndoRings colonoscopy followed by a standard colonoscopy displayed significantly lower polyp and adenoma miss rates, compared with patients who underwent the procedures in reverse order, according to a late-breaker presentation at Digestive Disease Week.

Researchers conducted a randomized colonoscopy study enrolling 96 patients who underwent an EndoRings colonoscopy (EC; EndoAid) followed by standard colonoscopy (SC; study group; n=49) or an SC followed by an EC (control group; n=47) between July 2013 and April 2014.

The EndoRings device is constructed of silicone rubber and is fitted onto the distal end of the colonoscope. During withdrawal, its rings help to mechanically stretch colonic folds, according to the researchers.

Forty-six adenomas were detected among patients who underwent EC first followed by seven adenomas during SC for the study group, compared with 17 adenomas followed by 19 more among control patients. The overall adenoma miss rate was 13% among study group patients (P<.01), compared with 53% of patients in the control group.

Polyp miss rates also were lower in patients who underwent EC first (11%), compared with patients who initially underwent SC (58%; P<.001). The removal of more polyps increased overall procedure time among patients who underwent EC first (22.1 minutes vs. 18 minutes; P<.01).

“This randomized tandem study demonstrates that colonoscopy with EndoRings is safe and has significantly lower adenoma and polyp miss rates as compared to standard colonoscopy,” Peter Siersema, MD, PhD, chief of the department of gastroenterology and hepatology, University Medical Center, Utrecht, Netherlands, said at the conference. - by Melinda Stevens

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Siersema PD. #929b. Presented at: Digestive Disease Week 2014; May 3-6; Chicago.

Disclosure: The researchers report numerous financial disclosures.