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Low BMD associated with IBD patients who underwent ostomy
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Patients with inflammatory bowel disease often had low bone mineral density after undergoing ostomy that resulted in five times more fragility fractures than patients with normal levels in a recent study.
Researchers at Cleveland Clinic retrospectively studied 126 patients (median age, 24.2 years; 55% women) diagnosed with IBD who had undergone ostomy and had at least one dual-energy X-ray absorptiometry (DEXA) after the procedure. Patients had Crohn’s disease (n=110) and ulcerative colitis (n=16), and the ostomies included ileostomy (n=120), colostomy (n=3) and jejunostomy (n=3).
Bo Shen
Bone mineral density (BMD) was measured with DEXA, and patients were stratified by normal or low BMD, based on International Society for Clinical Densitometry criteria. Thirty-seven patients (29.4%) were classified with low BMD at a median of 6.6 years after stoma creation.
“Low BMD was common in patients with IBD after ostomy, largely based on the findings in patients with CD with ileostomy,” the researchers said, noting that bone mass tended to stabilize during time after stoma. “Patients with IBD with ostomy must be considered as a high-risk population for bone loss. These patients should be closely monitored for BMD; particularly those at increased risk, such as those with a low BMI and history of fragility fractures.”
Disclosure: The researchers report no relevant financial disclosures.
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