November 13, 2012
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Standard, high-definition colonoscopy detection rates similar in community setting

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LAS VEGAS — High-definition colonoscopy did not significantly improve adenoma or polyp detection rates compared with standard-definition colonoscopy in a study presented at the 2012 American College of Gastroenterology Annual Scientific Meeting.

Researchers assessed the results from standard-definition colonoscopies (SDC) performed on 928 patients and from high-definition colonoscopies (HDC) in 1,466 patients to measure the impact of high-definition in detecting polyps and adenomas in a screening population of average-risk patients.

“High-resolution HDCs provide brighter and sharper images with a wider field of view than SDCs,” the researchers wrote. “This innovation is theoretically supposed to increase the endoscopist’s ability [to detect] clinically significant lesions in the colon. … However, the majority of current data are from large academic institutions and/or have heterogeneous patient groups that have included high-risk patients.”

Adenoma detection rates were 53.5% in the SDC group and 50.4% in the HDC group, while polyp detection rates were 32.6% in SDC and 30% in HDC. The differences between the groups were not statistically significant (P=.32 for adenomas and P=.3 for polyps). Demographic factors such as patient age (mean 59 years for each group, P=1.0), sex (44.5% males in the SDC group; 44.2% in the HDC group, P=.25) and ethnicity (46.3% African-American population in the SDC group; 46.2% in the HDC group, P=.9) were similar between groups, as was withdrawal time (mean 11.3 minutes for SDC; 12 minutes for HDC, P=.56).

“There’s not a huge difference, at least in far as adenoma and polyp detection, using different monitors,” researcher Asheesh Ray, MD, Digestive Disease Specialists in Hazelwood, Mo., told Healio.com. The investigators concluded that, despite the theoretical benefits of high-definition technology, it has yet to be proven whether HDC provides an advantage for a screening population in clinical practice.

For more information:

Ray A. P1046: High Definition vs. Standard Definition Colonoscopy for Polyp and Adenoma Detection in a Screening Population. A Comparison in a “Real-life Setting.” Presented at: the 2012 American College of Gastroenterology Annual Scientific Meeting; Oct. 19-24, Las Vegas.