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Statins may reduce risk of gastric cancer

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Statins may reduce the risk of gastric cancer, according to a study.

In a retrospective, population-based case-control study, researchers used the Taiwan National Health Insurance Research Database to review records of patients aged at least 50 years with an initial gastric cancer diagnosis between 2005 and 2008.

Among 337 gastric cancer patients and 1,348 controls, investigators found a 32% decrease in gastric cancer risk associated with any level of statin use (OR=0.68; 95% CI, 0.49-0.95). Gastric cancer risk tended to decrease with an increased statin dose (X² for linear trend=7.42, P=.006).

“Given the widespread use of statins, this magnitude of risk reduction would have a substantial public health impact,” the researchers wrote.

Disclosure: The research was supported in part by a grant from the National Science Council, Executive Yuan, Taiwan (NSC-96-2628-B-037-039-MY3).