Vasculitis Awareness

Rula Hajj-Ali, MD

Hajj-Ali reports consulting for AbbVie, Amgen and GlaxoSmithKline.
January 28, 2025
2 min watch
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VIDEO: Personalized approach necessary for vasculitis

Transcript

Editor's note: This is an automatically generated transcript, which has been slightly edited for clarity. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription.

Although we have done a lot of work in vasculitis, we still have so many things to do and there's so many unmet needs in vasculitis. The most important is that from a patient perspective, is that this is a understanding that this is a chronic condition. This is not just a one-time condition and this is something that has to be integrated in the needs of our patient and we have to think about personalized therapy. Not everything fit one. Everyone has a different aspect of vasculitis. Everyone have within the same vasculitis, it it present differently, different risk factor, et cetera. So we hope to get a personalized therapy.

We still need to look at glucocorticoid sparing strategies, which has been a big effort to do so, and we've seen multiple studies integrating a smaller dose and shorter duration of glucocorticoid, but we still need to work more on that. The major one is actually to have a novel predictive biomarkers to predict disease activities, relapses or remission, rather than keeping patient on a long-term medication. If we have biomarkers that can really precisely predict when we are gonna have a relapse, we can treat as needed and will decrease the comorbidities from a different immunotherapy, immunosuppression, and multiple other toxicity from medications.