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April 10, 2023
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Top in cardiology: SGLT2 inhibitor therapy; coordinated cardiovascular care

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Patients with heart failure who received an SGLT2 inhibitor were less likely to experience sudden cardiac death compared with those who received placebo, according to a study in Clinical Cardiology.

“The decreased incidence of sudden cardiac death in patients with [heart failure] receiving SGLT2 inhibitor therapy is directly concordant with studies demonstrating that SGLT2 inhibitor therapy has a profound impact on CV death and heart failure hospitalizations in patients with heart failure regardless of ejection fraction,” Connor Oates, MD, a cardiovascular disease fellow with MedStar Heart and Vascular Institute and Georgetown University-Washington Hospital Center, and colleagues wrote.

hands holding a heart
Patients with heart failure who received an SGLT2 inhibitor were less likely to experience sudden cardiac death compared with those who received placebo, data show. Image: Adobe Stock

It was the top story in cardiology last week.

Another top story was about a coordinated intervention in cardiology clinics that boosted prescriptions of guideline-recommended CVD and diabetes therapies. Researchers said they plan to scale this intervention across more cardiology clinics.

Read these and more top stories in cardiology below:

SGLT2 inhibitor therapy reduces sudden cardiac death risk in heart failure

SGLT2 inhibitor therapy in patients with heart failure is associated with a significantly lower incidence of sudden cardiac death vs. placebo, with the benefit persisting independent of other guideline-directed medical therapies. Read more.

Coordinated care can improve prescribing practices of recommended diabetes, CVD therapies

Implementing a coordinated care intervention in U.S. cardiology clinics led to a fourfold increase in the prescription of three groups of guideline-recommended therapies in adults with type 2 diabetes and atherosclerotic CVD. Read more.

Polypill for blood pressure lowering may improve adherence and reduce mortality

A renin-angiotensin system combination polypill to treat high BP was associated with improved adherence and lower all-cause mortality and cardiovascular event rates vs. taking multiple pills, researchers reported. Read more.

AI identifies reasons for statin nonuse in patients with diabetes at a single center

A deep learning model utilized unstructured electronic health record data to identify specific patient-, physician- and system-level reasons for statin nonuse among patients with diabetes, researchers reported. Read more.

Moderate exercise may be safe for patients with statin-related muscle pain

In a short-term study, researchers found no effect of statin therapy on self-reported muscle injury or symptoms after moderate exercise, regardless of whether patients were symptomatic at baseline. Read more.