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March 01, 2023
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Top in endocrinology: Testosterone therapy; hip fracture risk in type 2 diabetes

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Testosterone replacement therapy may help improve body composition in men with hypogonadism and prediabetes, according to findings published in Andrology.

“Experimental and clinical evidence clearly indicates that metabolic derangements even in preclinical stages are characterized by significantly lower testosterone circulating levels,” Giovanni Corona, MD, PhD, an endocrinologist and andrologist at Maggiore-Bellaria Hospital in Bologna, Italy, and colleagues wrote. “In the latter circumstances, testosterone replacement therapy can improve body composition, metabolic profiles and insulin resistance, whereas the data on body weight are more conflicting.”

Hip fracture
Adults with type 2 diabetes who use statins have a lower risk for hip fracture than those who do not use statins, data show. Image: Adobe Stock

It was the top story in endocrinology last week.

The second top story was about an association between statin use in adults with type 2 diabetes and a lower risk for hip fracture.

Read these and more top stories in endocrinology below:

Testosterone therapy may improve body composition, lipids for men with prediabetes

Testosterone replacement therapy combined with lifestyle modification may contribute to improved metabolic and glucose profiles for men with hypogonadism and prediabetes, according to a review article. Read more.

Hip fracture risk lower for adults with type 2 diabetes who use statins

Adults with type 2 diabetes who use statins have a lower risk for hip fracture than those who do not use statins, according to data published in Diabetes/Metabolism Research and Reviews. Read more.

Hybrid closed-loop systems present lower risk for severe hypoglycemia in type 1 diabetes

People with type 1 diabetes using a hybrid closed-loop insulin delivery system are less likely to experience severe hypoglycemia than nonusers, according to study data. Read more.

Quality improvement interventions reduce disparities with CGM use in type 1 diabetes

Interventions that incorporate shared decision-making, reduce racial-ethnic bias and provide language-specific instruction can reduce disparities with continuous glucose monitoring use in type 1 diabetes, according to two presenters. Read more.

Lower HbA1c, no decline in quality of life for adults with diabetic retinopathy

Adults with long-standing type 1 diabetes and proliferative diabetic retinopathy had worse functional vision than controls without diabetes, but no decline in quality of life was observed from 2007 to 2019, according to study findings. Read more.