Top in GI: Roux-en-Y gastric bypass; guidance on subepithelial lesions
Patients who undergo Roux-en-Y gastric bypass may be more sensitive to alcohol exposure compared with those who undergo sleeve gastrectomy and a weight management program, according to a recent study.
“Restrictive procedures, such as sleeve gastrectomy or gastric banding and mixed restrictive or malabsorptive procedures, such as Roux-en-Y gastric bypass, are effective in promoting weight loss and reversing underlying metabolic comorbidities, but they may induce differential alterations in alcohol metabolism,” Nadim Mahmud, MD, MS, MPH, MSCE, an assistant professor of medicine and epidemiology at University of Pennsylvania Perelman School of Medicine, and colleagues wrote in JAMA Surgery.

It was the top story in gastroenterology last week.
Another top story covered new guidelines from the American College of Gastroenterology on the diagnosis and management of patients with gastrointestinal subepithelial lesions.
Read these and more top stories in gastroenterology below:
Roux-en-Y tied to increased risk for hospitalization related to alcohol-use disorder
Roux-en-Y gastric bypass was associated with an increased risk for alcohol-use disorder-related hospitalization compared with sleeve gastrectomy and a weight management program, according to research published in JAMA Surgery. Read more.
ACG guides diagnosis, management of subepithelial GI lesions with new recommendations
The ACG has developed a clinical guideline to aid physicians in the diagnosis and management of patients with gastrointestinal subepithelial lesions, which recently was published in The American Journal of Gastroenterology. Read more.
Targeted decision aids may not impact CRC screening preference among older adults
Although decision aids helped inform older adults about potential benefits and risks associated with colorectal cancer screening, the tools did not significantly influence patient preference for screening, regardless of health. Read more.
Q&A: Gravity’s role in IBS pathogenesis, symptoms: A new hypothesis
Irritable bowel syndrome may result from ineffective anatomical, physiological and neuropsychological gravity-management systems, a researcher theorized in an article published in The American Journal of Gastroenterology. Read more.
FMT not linked to weight loss outcomes in patients undergoing bariatric surgery
Fecal microbiota transplantation 6 months before bariatric surgery did not reduce body weight in a small cohort of patients with obesity in Finland, according to study results published in JAMA Network Open. Read more.