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July 02, 2021
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Top in rheumatology: Tocilizumab granted EUA, ACR warns against home infusions

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The FDA authorized the emergency use of tocilizumab for certain hospitalized patients with COVID-19. This marks the fourth monoclonal antibody authorized during the pandemic.

However, it was not authorized for outpatients with COVID-19. The announcement was the top story in rheumatology last week.

U.S. Food and Drug Administration
The FDA has issued an emergency use authorization for tocilizumab to treat hospitalized patients who are receiving systemic corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation or extracorporeal membrane oxygenation. Source: Adobe Stock

Another top story was about a position statement from the American College of Rheumatology, which said that requiring patients to do biologic infusions at home jeopardizes their safety. The ACR said biologics can cause a range of reactions.

Read these and more top stories in rheumatology below:

FDA issues EUA for tocilizumab to treat patients hospitalized with COVID-19

The FDA has issued an emergency use authorization for tocilizumab to treat hospitalized patients receiving corticosteroids who require supplemental oxygen, mechanical ventilation or extracorporeal membrane oxygenation, according to a press release. Read more.

ACR: Infusions belong in a facility, not at home

The American College of Rheumatology has released an updated position statement declaring biologic infusions should be administered in a monitored health care setting rather than in the patient’s home, as some insurers have mandated. Read more.

In for the long haul: Clinicians wrestle with post-acute COVID-19 syndromes

The time warp of COVID-19 has offered yet another twist. As acute infections and the associated fatalities have finally begun to ebb in the United States, a new phase of the pandemic has emerged: the long-hauler phase. Read more.

Tofacitinib lowers risks for death, respiratory failure in COVID-19 pneumonia

Treatment with tofacitinib led to a lower risk for death or respiratory failure through day 28, compared with placebo, in patients hospitalized with COVID-19 pneumonia, according to data published in The New England Journal of Medicine. Read more.

Sprifermin maintains long-term cartilage structural improvements in knee osteoarthritis

Improvements in articular cartilage thickness among patients with knee osteoarthritis who received sprifermin, versus placebo, during the FORWARD trial were maintained over a 3.5- to 4-year follow-up period, according to data. Read more.