Top in endocrinology: Low-calorie keto diet, FDA panel’s stance on teplizumab
New study findings show that a low-calorie ketogenic diet can have a significant effect on weight loss, testosterone levels and insulin resistance among men with overweight or obesity. It was the top story in endocrinology last week.
Another top story was about an FDA panel’s recommendation to approve teplizumab (Provention Bio), which was shown in a randomized clinical trial to delay the development of type 1 diabetes in children.
Read these and more top stories in endocrinology below:
Low-calorie ketogenic diet boosts testosterone for men with obesity
A very low-calorie ketogenic diet promotes a dramatic and early effect on insulin resistance and testosterone levels among men with overweight or obesity, according to a small study presented at the European Congress of Endocrinology. Read more.
FDA advisory committee recommends approval of immunotherapy to delay type 1 diabetes
An FDA advisory panel voted 10-7 in favor of recommending approval of teplizumab to delay development of type 1 diabetes in high-risk children and adults, with most committee members expressing some concerns about trial size and safety. Read more.
Organizations must lead in boosting well-being, reducing burnout among physicians
Health care organizations must take steps to reduce burnout and enhance the well-being of physicians, according to a keynote speaker at the American Association of Clinical Endocrinology virtual meeting. Read more.
Gestational diabetes may predict autoimmune diabetes risk
Women diagnosed with gestational diabetes are more likely to be autoantibody positive and develop type 1 diabetes in the decade after delivery compared with pregnant women without gestational diabetes, data from a large Finnish cohort show. Read more.
Disparities growing in pediatric diabetes technology use, HbA1c in US
Socioeconomic disparities in diabetes technology use and HbA1c widened among children in the United States in 2016-2018 compared with 2010-2012, according to a study published in Diabetes Care. Read more.