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April 07, 2021
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Top in endocrinology: NASH treatment, ovarian function in early menopause

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Results from a phase 1B/2A trial showed that a long-acting glycopegylated fibroblast growth factor 21 analog reduced liver fat and triglycerides in adults with nonalcoholic steatohepatitis. It was the top story in endocrinology last week.

Another top story was about a pilot study investigating ovarian function in early menopause. In a cohort of 12 early menopausal women, 11 resumed their menstrual cycle a little more than 1 month after receiving an injection of platelet-rich plasma and recombinant follicle-stimulating hormone in the extended subcortical area of the bilateral ovaries.

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Source: Adobe Stock

Read these and more top stories in endocrinology below:

BIO89-100 reduces liver fat, lowers triglycerides in adults with NASH

BIO89-100 reduced liver fat in adults with nonalcoholic steatohepatitis, or NASH, while also lowering triglycerides for participants taking weekly and biweekly doses, according to trial data presented at the ENDO annual meeting. Read more.

Platelet-rich plasma may restore ovarian function in early menopause

An injection of platelet-rich plasma and gonadotropins near the ovarian follicles may help restore ovarian function for early menopausal women, according to data from a pilot study published in Menopause. Read more.

Medical history may help predict COVID-19 risk in people with diabetes

A prediction model factoring in recent hospitalizations, comorbidities and drug exposure may help determine the individual risk for COVID-19 critical care admission and mortality for people with diabetes, according to study data. Read more.

Strategies for surveillance after thyroid cancer ‘cure’ based on treatment type

Surveillance after treatment for low-risk thyroid cancer is a balancing act that must consider treatment modality and patient concerns about recurrence, but several considerations can help stratify who should receive follow-up screenings. Read more.

Learning science theory can improve remote delivery of diabetes survival-skills education

Learning science theory can yield new strategies to allow providers to improve the remote delivery of diabetes survival-skills education, according to a presenter at the ENDO annual meeting. Read more.