Top stories in endocrinology: Insulin patch effective in type 2 diabetes; type 1 diabetes, obesity may increase adverse CV outcomes

Among the top stories in endocrinology last week were findings that determined an insulin patch can safely provide similarly effective glycemic management in adults with type 2 diabetes compared with a standard insulin pen and a study that found adults with type 1 diabetes and overweight or obesity may be more susceptible to cardiovascular disease, heart failure and higher mortality risk compared with those of lower weight status.

Other highlights included research that concluded red blood cell variance from liver disease alters HbA1c readings, a study that found continuous glucose monitoring data and machine-learning techniques revealed dysglycemia phenotypes in type 1 diabetes and data presented at the European Congress on Obesity that suggested bariatric surgery may increase risk for pregnancy and birth complications.

Insulin patch proves effective for adults with type 2 diabetes

An insulin patch can safely provide similarly effective glycemic management in adults with type 2 diabetes compared with a standard insulin pen, according to findings published in Diabetes Technology & Therapeutics. Read more.

‘Obesity paradox’ challenged in type 1 diabetes

Adults with type 1 diabetes and overweight or obesity may be more susceptible to cardiovascular disease, heart failure and higher mortality risk compared with those of lower weight status, according to findings published in Diabetes Care. Read more.

Red blood cell variance from liver disease alters HbA1c readings

When treating adults with diabetes and liver disease who are being evaluated for transplant, HbA1c should not be used to determine blood glucose level, according to findings published in Diabetic Medicine. Read more.

Continuous glucose monitoring, machine learning reveal dysglycemia phenotypes in type 1 diabetes

Researchers have identified three distinct patterns of dysglycemia in adolescents with type 1 diabetes using a combination of blinded continuous glucose monitoring data and machine-learning techniques, offering clinicians an opportunity to better tailor therapy, according to findings published in Pediatric Diabetes. Read more.

Bariatric surgery may increase risk for pregnancy, birth complications

Women who become pregnant after bariatric surgery are nearly three times more likely to deliver an infant small for gestational age when compared with women who did not undergo surgery. Bariatric surgery was also associated with increased risks for preterm birth, perinatal mortality and congenital abnormalities, according to data presented at the European Congress on Obesity. Read more.