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Top stories in infectious disease: FDA approves new HIV regimen, reliance on pre-exposure prophylaxis may increase risk for STIs
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Among the top stories in infectious disease last week were the FDA approval of the first complete two-drug HIV regimen for antiretroviral therapy-naive adults and a study that found the use of pre-exposure prophylaxis for HIV prevention was associated with an increase in the incidence of sexually transmitted infections among gay and bisexual men.
Other highlights included research that suggested the IV formulation of fosfomycin was effective in treating complicated UTIs, data that indicated a jet injector was effective and efficient for delivering the flu vaccine and the World Health Organization’s declaration that the Ebola outbreak in the Democratic Republic of the Congo is still not an international health emergency.
FDA approves first two-drug HIV regimen for antiretroviral therapy-naive adults
The FDA has approved Dovato, the first complete two-drug HIV regimen for antiretroviral therapy-naive adults. Read more.
Pre-exposure prophylaxis associated with increase in STIs among gay, bisexual men
The use of pre-exposure prophylaxis for HIV prevention was associated with an increase in the incidence of sexually transmitted infections among gay and bisexual men during a multi-year study conducted in Australia, according to findings published in JAMA. Read more.
IV fosfomycin effective in treating complicated UTIs
The IV formulation of fosfomycin was found to be effective in treating complicated UTIs, including acute pyelonephritis, compared with IV piperacillin-tazobactam, according to research published in Clinical Infectious Diseases. Read more.
Jet injector effective and efficient for delivering flu vaccine
The Med-Jet H4, a needle-free device for delivering seasonal influenza vaccine, is attractive to patients, is rapidly learned by nurses and generates similar responses to all vaccine strains as a traditional intramuscular injection, according to study data presented at the National Foundation for Infectious Diseases’ Annual Conference on Vaccinology Research. Read more.
World Health Organization says Ebola outbreak still not an international health emergency
For the second time in 6 months, an emergency committee convened by WHO voted against declaring the Ebola virus outbreak in the Democratic Republic of the Congo an international public health emergency. Read more.