This article is more than 5 years old. Information may no longer be current.
Top stories in endocrinology: Lilly announces plan for generic rapid-acting insulin, teprotumumab reduces proptosis
Click Here to Manage Email Alerts
Among the top stories in endocrinology last week were Eli Lilly’s announcement that it will introduce an authorized generic version of insulin lispro injection in the United States and trial results that suggested more patients with active thyroid eye disease assigned teprotumumab experienced a meaningful improvement in proptosis compared with those assigned a placebo.
Other highlights included a report that indicated that isolated female-pattern hair loss may not signal hyperandrogenism, expert recommendations for a gradual transition toward diabetes self-management for adolescents and their families and a study that found women diagnosed with gestational diabetes were twice as likely to experience a cardiovascular event postpartum compared with women with normoglycemia during pregnancy.
Lilly announces plan for generic rapid-acting insulin
Eli Lilly announced it will introduce an authorized generic version of insulin lispro injection in the United States, promising a list price that is 50% lower than the current Humalog list price, according to a press release from the company. Read more.
Thyroid eye disease drug meets primary endpoint for proptosis reduction
Top-line results from the OPTIC trial showed that the phase 3 study met its primary endpoint, demonstrating that more patients with active thyroid eye disease assigned teprotumumab experienced a meaningful improvement in proptosis, or protrusion of the eyeball, compared with patients assigned placebo, according to a press release from Horizon Pharma. Read more.
Isolated female-pattern hair loss may not signal hyperandrogenism
Most women who exhibit a frontal-central pattern of hair loss have normal circulating androgen concentrations and an absence of other androgen-related signs or symptoms, although the condition is observed in as many as 30% of women with polycystic ovary syndrome, according to a report from the Androgen Excess and PCOS Society published in The Journal of Clinical Endocrinology & Metabolism. Read more.
Experts recommend gradual transition toward diabetes self-management for adolescents, families
Navigating adolescence can be tough for any young person and their parents, but children and teens with diabetes face additional challenges in the transition to adulthood. The partnership between parent and child will change as the child becomes more confident and motivated to manage his or her own condition. Read more.
Gestational diabetes doubles risk for CVD
Women diagnosed with gestational diabetes are twice as likely to experience a cardiovascular event postpartum compared with women with normoglycemia during pregnancy, with the greatest risk observed in the first decade after giving birth, according to findings from a meta-analysis published in Diabetologia. Read more.