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Smoking interferes with assisted fertilization procedures
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Smoking increased the odds an assisted reproductive technology procedure involving embryos within the body was cancelled, according to findings recently published in the Journal of Women’s Health.
“The associations between smoking and [assisted reproductive technology] clinical outcomes have not been examined using population-based data,” Karilynn Rockhill, MPH, of the CDC’s division of reproductive health and colleagues wrote.
Researchers analyzed previously existing data on more than 12,000 assisted reproductive technology cycles that were exposed to smoking from 2009 to 2013.
They found smoking was associated with higher adjusted odds of cycle cancellation within the body without an embryo transfer (aOR = 1.1; 95% CI, 1-1.21) and cancellations within the body before fresh oocyte retrieval or frozen embryo transfer (aOR = 1.11; 95% CI, 1.02-1.21).
In addition, the smokers were more likely to be non-Hispanic white, younger, multigravida and have higher proportions of tubal disease and a male partner who was infertile vs. the nonsmokers.
“Providers should discuss the effects of smoking on infertility and benefits of smoking cessation and provide support and effective interventions that will help women enter assisted reproductive technology treatments tobacco free,” Rockhill and colleagues concluded. – by Janel Miller
Disclosures: Healio Primary Care Today was unable to determine authors’ relevant financial disclosures prior to publication.