Top stories in gastroenterology: Predictors of adverse events after endoscopic retrograde cholangiopancreatography, olorinab effective for Crohn’s disease

The most-read story in gastroenterology last week was a study where procedure volume was found to be predictive of adverse events after endoscopic retrograde cholangiopancreatography at a health care facility.

Other popular stories included a phase 2a study that found olorinab was safe and effective in patients with Crohn’s disease, a study that showed how rifaximin helped patients with Clostridium difficile who had already undergone a previous treatment for the infection, a report detailing how two colonoscopy techniques faired in detecting adenomas, and a model that predicted mortality in patients with ulcerative colitis. – by Janel Miller

Procedure volume predictive of adverse events following endoscopic retrograde cholangiopancreatography

The volume of endoscopic retrograde cholangiopancreatography procedures done at a health care facility was a strong predictor of risk for unplanned hospital encounters following a procedure, according to research published in Gastroenterology. Read more.

Olorinab appears safe, effective for Crohn’s associated chronic pain

Data from a phase 2a study centered on APD371 showed positive safety and efficacy results for the treatment of Crohn’s disease associated with chronic abdominal pain. Read more.

‘Follow-on’ rifaximin reduc es Clostridium difficile infection, effect estimate lacks precision

Taking rifaximin following initial treatment for Clostridium difficile infection helped patients prevent recurrent disease, according to research published in Gut. Read more.

Second forward, retroflexed views improve right-sided adenoma detection

Two colonoscopy techniques designed to provide a better view in the right side of the colon both improved adenoma detection over standard colonoscopy withdrawal, according to research published in Gastrointestinal Endoscopy. Read more.

Ulcerative colitis index severity score, early readmission predict mortality

A model stratifying the severity of hospitalization and identify colectomy risks, when used with early hospital readmission, helped predict increased mortality among patients with ulcerative colitis, according to research published in Inflammatory Bowel Diseases. Read more.