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Top stories in gastroenterology: FDA clears slim colonoscopy device; marital discord leads to ‘leaky gut’
Among the top stories in gastroenterology this week was the FDA approval of a device that can assist doctors performing slim colonoscopies and a study that found fights with one’s spouse caused inflammation that led to increased gut permeability.
Other top stories included reports that described the impact a vedolizumab combination therapy had on the majority of patients with ulcerative colitis, results from patients who underwent a second sigmoidoscopy for acute severe ulcerative colitis, and what led patients with irritable bowel syndrome to experience physiological phenomenon where a painful stimulus inhibited another existing pain. – by Janel Miller
FDA clears new device to aid slim colonoscopy procedures
The FDA has issued 501(k) clearance to Motus GI Holdings Inc. for the commercialization of a novel device that is compatible with smaller diameter and more flexible slim colonoscopes with additional enhancements to Motus’ low friction lubricious coating technology to aid in navigation through the colon, according to a company press release. Read more.
Marital arguments can lead to a ‘leaky gut’
Getting into a heated argument with a spouse can cause inflammation that leads to increased gut permeability, according to research published in Psychoneuroendocrinology. Read more.
Vedolizumab combination therapy helps ulcerative colitis patients avoid colectomy
More than two-thirds of patients with ulcerative colitis treated with a calcineurin inhibitor in combination with Entyvio experienced colectomy-free survival for a year, according to research published in Clinical Gastroenterology and Hepatology. Read more.
‘Second-look’ sigmoidoscopy helps predict colectomy rate in acute severe ulcerative colitis
Patients hospitalized for acute severe ulcerative colitis who show endoscopic improvement after undergoing a second sigmoidoscopy have lower rates of colectomy, according to research published in Inflammatory Bowel Diseases. Read more.
Diminished condition pain modulation observed in patients with irritable bowel syndrome
Patients with irritable bowel syndrome experienced significantly diminished conditioned pain modulation, a physiological phenomenon where a painful stimulus can inhibit another existing pain, according to research published in Alimentary Pharmacology and Therapeutics. Read more.