Top stories in endocrinology: Recommended upper limits of vitamin D, calcium linked to hypercalcuria; fish oil enhances early childhood growth

Among the top stories in endocrinology this week was a trial that showed an association between hypercalcuria and the upper-limit intakes of vitamin D and calcium recommended by the Endocrine Society, and a report that indicated fish oil improves growth in children up to 6 years of age.

Other top stories included reports on the impact of combining two different medical societies’ classifications in patients with thyroid cancer, the positive results of taking coenzyme Q10 plus vitamin E supplementation in women with polycystic ovary syndrome, and the potential impact of adults with type 2 diabetes taking proton pump inhibitors and histamine-2 receptor antagonists to treat gastroesophageal reflux disease. - by Janel Miller

Recommended upper limits of vitamin D, calcium associated with hypercalcuria

The upper-limit intake for vitamin D recommended by the Endocrine Society, when coadministered with calcium intake at the upper recommended level, is associated with increased odds for hypercalciuria when compared against recommendations from the Institute of Medicine, according to findings from a randomized, double-blind controlled trial. Read more.

Fish oil can improve early childhood growth

The use of fish oil supplements during the third trimester of pregnancy has been shown to increase children’s lean mass, bone mass and fat mass, but not obesity, in the first 6 years of life, according to a study in The BMJ. Read more.

CoQ10 plus vitamin E improves metabolic profile in PCOS

Women with polycystic ovary syndrome randomly assigned to 8 weeks of coenzyme Q10 plus vitamin E supplementation experienced an improvement in glycemic and anthropometric measures vs. women assigned to either supplement alone, according to findings published in The Journal of Clinical Endocrinology and Metabolism. Read more.

GLP-1-related nausea associated with acid reflux medications

Use of proton pump inhibitors and histamine-2 receptor antagonists to treat gastroesophageal reflux disease or to counter gastric effects of NSAIDs is a risk factor for nausea and vomiting in adults with type 2 diabetes prescribed GLP-1 receptor agonists, according to a retrospective study published in the Journal of Diabetes Investigation. Read more.

Combining American Joint Committee on Cancer, American Thyroid Association cancer classifications provide more patient-specific outlooks

Combining the eighth edition of the American Joint Committee on Cancer staging system and the American Thyroid Association risk classification system can provide more precise estimates of recurrence risk and disease-specific survival for patients with thyroid cancer, according to findings published in Thyroid. Read more.