September 07, 2018
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Top gastroenterology stories: Believing IBS is a disease of ‘anxious women’ is ‘wrong,’ vedolizumab linked to low immunogenicity

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The top story in gastroenterology this week was a Healio exclusive report on how believing irritable bowel syndrome is a disease of ‘nervous, anxious women’ is ‘antiquated’ and ‘wrong.’

Other top stories included studies that found that patients on vedolizumab therapy have low immunogenicity, menopausal hormone therapy is linked to microscopic colitis, endoscopic sleeve gastroplasty is associated with less weight loss and interval colorectal cancer is not more lethal than clinically detected disease.

Q&A: Believing IBS is a disease of ‘nervous, anxious women’ is ‘antiquated’ and ‘wrong’

Healio Gastroenterology and Liver Disease spoke with Mark Pimentel, MD, executive director of the Medically Associated Science and Technology (MAST) Program at Cedars Sinai Medical Center, about his reaction to a doctor labeling irritable bowel syndrome as a “disease of nervous and anxious women,” the problems associated with those beliefs, and how to try to better educate physicians. Read more.

Low immunogenicity among patients on vedolizumab therapy

Researchers found a low rate of immunogenicity among patients with inflammatory bowel disease undergoing Entyvio therapy, as well as a link between high drug trough levels and normal C-reactive protein in patients with Crohn’s disease, according to a study published in Inflammatory Bowel Diseases. Read more.

Menopausal hormone therapy linked to microscopic colitis

Women who undergo menopausal hormone therapy appear to have a higher risk for developing microscopic colitis, according to data from a large, nationwide cohort study published in Gastroenterology. Read more.

Less weight loss, adverse events with endoscopic sleeve gastroplasty

Patients who underwent endoscopic sleeve gastroplasty lost less weight in the first 6 months following surgery than patients who underwent a common laparoscopic procedure, according to research published in Gastrointestinal Endoscopy. Read more.

Interval colorectal cancer not more lethal than clinically detected disease

Patients with interval colorectal cancers have a similar risk for mortality as patients with clinically detected colorectal cancers, according to research published in Gastroenterology. Read more.