Top stories in hematology/ oncology: Pathogenic variant linked to triple-negative breast cancer, FDA grants breakthrough device designation to cancer-detecting blood test

Among the top stories in hematology and oncology is a study that found multigene hereditary cancer panel testing can identify women at increased risk for triple-negative breast cancer based on mutations in certain genes.

Another top story includes the FDA breakthrough device designation grant to the PapGene liquid biopsy test for the detection of cancer among older adults.

Other top stories include a substudy that showed compression hosiery improved quality of life and appeared cost-effective, an FDA approval of mogamulizaumab-kpkc injection for the treatment of relapsed or refractory mycosis fungoides and Sézary syndrome, and findings that showed few individuals reported being aware of the association between insufficient physical activity and increased risk for cancer.

Researchers identify pathogenic variant linked to triple-negative breast cancer

Multigene hereditary cancer panel testing can identify women at increased risk for triple-negative breast cancer based on mutations in BARD1, BRCA1, BRCA2, PALB2 and RAD51D, according to study findings. Read More.

FDA grants breakthrough device designation to cancer-detecting blood test

The FDA granted the PapGene liquid biopsy test breakthrough device designation for the detection of cancer among people aged older than 65 years, according to the manufacturer. Read More.

Compression hosiery preferred option for acute deep vein thrombosis

Compression hosiery improved quality of life and appeared cost-effective for the acute phase between diagnosis of deep vein thrombosis and application of elastic compression stockings, according to results of a substudy of the IDEAL DVT study. Read More.

FDA approves Poteligeo for mycosis fungoides, Sézary syndrome

The FDA approved mogamulizumab-kpkc injection for the treatment of adults with relapsed or refractory mycosis fungoides and Sézary syndrome after at least one prior systemic therapy. Read More.

Public lacks awareness of link between physical activity, cancer risk

Few individuals reported being aware of the association between insufficient physical activity and increased risk for cancer, according to findings from a cross-sectional survey.