Top stories in infectious disease: FDA recommends omadacyline for approval, new antimicrobials demonstrate ‘good activity’

Among the top stories in infectious disease is the vote by the FDA’s Antimicrobials Drug Advisory Committee in favor of approving a new antibiotic for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.

Another top story includes a report on how two new antimicrobials with potential utility for resistant isolates demonstrated different in vitro activities against certain bacterium.

Other top stories include a new Ebola outbreak in the Democratic Republic of the Congo that is unrelated to the outbreak that was declared over just 2 weeks ago, a link between obesity and the duration of influenza A shedding time in adults, and a study that found that almost 10% of patients with candidemia also had a Clostridium difficile infection coinfection.

FDA committee recommends omadacycline for approval

The FDA’s Antimicrobials Drug Advisory Committee has voted in favor of approving Paratek’s new antibiotic omadacycline for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia, the company announced. Read More.

New antimicrobials demonstrate ‘good activity’ at long-term acute-care hospitals

Two new antimicrobials with potential utility for resistant isolates at long-term acute-care hospitals demonstrated different in vitro activities against ceftazidime-nonsusceptible Pseudomonas aeruginosa and carbapenem-resistant Enterobacteriaceae, or CRE, according to research findings published in Clinical Microbiology and Infectious Diseases. Read More.

Vaccine can be used in new Ebola outbreak in Congo, WHO says

WHO confirmed today that the latest Ebola virus outbreak in the Democratic Republic of the Congo, or DRC, is unrelated to the previous outbreak that was declared over just 2 weeks ago. Read More.

Obesity nearly doubles duration of influenza A virus shedding in adults

Researchers have determined a link between obesity and the duration of influenza A shedding time in adults, finding it almost doubles the length of virus shedding. Read More.

Patients with candidemia have significant risk for CDI coinfection

Almost 10% of patients with candidemia also had a Clostridium difficile infection coinfection, according to a recent study. Read More.